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Colorectal cancer, susceptibility to

MedGen UID:
346821
•Concept ID:
C1858438
•
Finding
Synonyms: COLORECTAL CANCER, SUSCEPTIBILITY TO; Susceptibility to colorectal cancer
 
OMIM®: 168461; 603028; 604373

Professional guidelines

PubMed

The Contribution of MMP-7 Genotypes to Colorectal Cancer Susceptibility in Taiwan.
Yueh TC, Wu CN, Hung YW, Chang WS, Fu CK, Pei JS, Wu MH, Lai YL, Lee YM, Yen ST, Li HT, Tsai CW, Bau DT
Cancer Genomics Proteomics 2018 May-Jun;15(3):207-212. doi: 10.21873/cgp.20079. PMID: 29695403Free PMC Article
When and how to perform genetic testing for inherited colorectal cancer syndromes.
Lynch PM
J Natl Compr Canc Netw 2013 Dec 1;11(12):1577-83. doi: 10.6004/jnccn.2013.0181. PMID: 24335689
SULT1A1 genotype and susceptibility to colorectal cancer.
Lilla C, Risch A, Verla-Tebit E, Hoffmeister M, Brenner H, Chang-Claude J
Int J Cancer 2007 Jan 1;120(1):201-6. doi: 10.1002/ijc.22156. PMID: 17013894

Curated

UK NICE Guideline NG151, Colorectal cancer, 2021

Recent clinical studies

Etiology

The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection.
Patel SG, Karlitz JJ, Yen T, Lieu CH, Boland CR
Lancet Gastroenterol Hepatol 2022 Mar;7(3):262-274. Epub 2022 Jan 26 doi: 10.1016/S2468-1253(21)00426-X. PMID: 35090605
Novel Diagnostic Biomarkers in Colorectal Cancer.
Zygulska AL, Pierzchalski P
Int J Mol Sci 2022 Jan 13;23(2) doi: 10.3390/ijms23020852. PMID: 35055034Free PMC Article
Role of oncogenic KRAS in the prognosis, diagnosis and treatment of colorectal cancer.
Zhu G, Pei L, Xia H, Tang Q, Bi F
Mol Cancer 2021 Nov 6;20(1):143. doi: 10.1186/s12943-021-01441-4. PMID: 34742312Free PMC Article
Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer.
Mármol I, Sánchez-de-Diego C, Pradilla Dieste A, Cerrada E, Rodriguez Yoldi MJ
Int J Mol Sci 2017 Jan 19;18(1) doi: 10.3390/ijms18010197. PMID: 28106826Free PMC Article
Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer.
Pearlman R, Frankel WL, Swanson B, Zhao W, Yilmaz A, Miller K, Bacher J, Bigley C, Nelsen L, Goodfellow PJ, Goldberg RM, Paskett E, Shields PG, Freudenheim JL, Stanich PP, Lattimer I, Arnold M, Liyanarachchi S, Kalady M, Heald B, Greenwood C, Paquette I, Prues M, Draper DJ, Lindeman C, Kuebler JP, Reynolds K, Brell JM, Shaper AA, Mahesh S, Buie N, Weeman K, Shine K, Haut M, Edwards J, Bastola S, Wickham K, Khanduja KS, Zacks R, Pritchard CC, Shirts BH, Jacobson A, Allen B, de la Chapelle A, Hampel H; Ohio Colorectal Cancer Prevention Initiative Study Group
JAMA Oncol 2017 Apr 1;3(4):464-471. doi: 10.1001/jamaoncol.2016.5194. PMID: 27978560Free PMC Article

Diagnosis

Young-onset colorectal cancer.
Spaander MCW, Zauber AG, Syngal S, Blaser MJ, Sung JJ, You YN, Kuipers EJ
Nat Rev Dis Primers 2023 Apr 27;9(1):21. doi: 10.1038/s41572-023-00432-7. PMID: 37105987Free PMC Article
The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection.
Patel SG, Karlitz JJ, Yen T, Lieu CH, Boland CR
Lancet Gastroenterol Hepatol 2022 Mar;7(3):262-274. Epub 2022 Jan 26 doi: 10.1016/S2468-1253(21)00426-X. PMID: 35090605
Novel Diagnostic Biomarkers in Colorectal Cancer.
Zygulska AL, Pierzchalski P
Int J Mol Sci 2022 Jan 13;23(2) doi: 10.3390/ijms23020852. PMID: 35055034Free PMC Article
Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies.
Keum N, Giovannucci E
Nat Rev Gastroenterol Hepatol 2019 Dec;16(12):713-732. Epub 2019 Aug 27 doi: 10.1038/s41575-019-0189-8. PMID: 31455888
Early-onset colorectal cancer in young individuals.
Mauri G, Sartore-Bianchi A, Russo AG, Marsoni S, Bardelli A, Siena S
Mol Oncol 2019 Feb;13(2):109-131. Epub 2018 Dec 22 doi: 10.1002/1878-0261.12417. PMID: 30520562Free PMC Article

Therapy

Tumor-Infiltrating Lymphocytes in Colorectal Cancer: The Fundamental Indication and Application on Immunotherapy.
Bai Z, Zhou Y, Ye Z, Xiong J, Lan H, Wang F
Front Immunol 2021;12:808964. Epub 2022 Jan 14 doi: 10.3389/fimmu.2021.808964. PMID: 35095898Free PMC Article
Role of oncogenic KRAS in the prognosis, diagnosis and treatment of colorectal cancer.
Zhu G, Pei L, Xia H, Tang Q, Bi F
Mol Cancer 2021 Nov 6;20(1):143. doi: 10.1186/s12943-021-01441-4. PMID: 34742312Free PMC Article
Rising incidence of early-onset colorectal cancer - a call to action.
Akimoto N, Ugai T, Zhong R, Hamada T, Fujiyoshi K, Giannakis M, Wu K, Cao Y, Ng K, Ogino S
Nat Rev Clin Oncol 2021 Apr;18(4):230-243. Epub 2020 Nov 20 doi: 10.1038/s41571-020-00445-1. PMID: 33219329Free PMC Article
Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies.
Keum N, Giovannucci E
Nat Rev Gastroenterol Hepatol 2019 Dec;16(12):713-732. Epub 2019 Aug 27 doi: 10.1038/s41575-019-0189-8. PMID: 31455888
Recent advances in Lynch syndrome.
Biller LH, Syngal S, Yurgelun MB
Fam Cancer 2019 Apr;18(2):211-219. doi: 10.1007/s10689-018-00117-1. PMID: 30627969Free PMC Article

Prognosis

Young-onset colorectal cancer.
Spaander MCW, Zauber AG, Syngal S, Blaser MJ, Sung JJ, You YN, Kuipers EJ
Nat Rev Dis Primers 2023 Apr 27;9(1):21. doi: 10.1038/s41572-023-00432-7. PMID: 37105987Free PMC Article
The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection.
Patel SG, Karlitz JJ, Yen T, Lieu CH, Boland CR
Lancet Gastroenterol Hepatol 2022 Mar;7(3):262-274. Epub 2022 Jan 26 doi: 10.1016/S2468-1253(21)00426-X. PMID: 35090605
Colorectal Cancer Epidemiology: Recent Trends and Impact on Outcomes.
Baidoun F, Elshiwy K, Elkeraie Y, Merjaneh Z, Khoudari G, Sarmini MT, Gad M, Al-Husseini M, Saad A
Curr Drug Targets 2021;22(9):998-1009. doi: 10.2174/1389450121999201117115717. PMID: 33208072
Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies.
Keum N, Giovannucci E
Nat Rev Gastroenterol Hepatol 2019 Dec;16(12):713-732. Epub 2019 Aug 27 doi: 10.1038/s41575-019-0189-8. PMID: 31455888
Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer.
Mármol I, Sánchez-de-Diego C, Pradilla Dieste A, Cerrada E, Rodriguez Yoldi MJ
Int J Mol Sci 2017 Jan 19;18(1) doi: 10.3390/ijms18010197. PMID: 28106826Free PMC Article

Clinical prediction guides

Young-onset colorectal cancer.
Spaander MCW, Zauber AG, Syngal S, Blaser MJ, Sung JJ, You YN, Kuipers EJ
Nat Rev Dis Primers 2023 Apr 27;9(1):21. doi: 10.1038/s41572-023-00432-7. PMID: 37105987Free PMC Article
Potential Role of the Gut Microbiome In Colorectal Cancer Progression.
Kim J, Lee HK
Front Immunol 2021;12:807648. Epub 2022 Jan 7 doi: 10.3389/fimmu.2021.807648. PMID: 35069592Free PMC Article
The aging-related risk signature in colorectal cancer.
Yue T, Chen S, Zhu J, Guo S, Huang Z, Wang P, Zuo S, Liu Y
Aging (Albany NY) 2021 Feb 26;13(5):7330-7349. doi: 10.18632/aging.202589. PMID: 33658390Free PMC Article
Crosstalk Between the MSI Status and Tumor Microenvironment in Colorectal Cancer.
Lin A, Zhang J, Luo P
Front Immunol 2020;11:2039. Epub 2020 Aug 12 doi: 10.3389/fimmu.2020.02039. PMID: 32903444Free PMC Article
Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer.
Mármol I, Sánchez-de-Diego C, Pradilla Dieste A, Cerrada E, Rodriguez Yoldi MJ
Int J Mol Sci 2017 Jan 19;18(1) doi: 10.3390/ijms18010197. PMID: 28106826Free PMC Article

Recent systematic reviews

Mosaicism in Patients With Colorectal Cancer or Polyposis Syndromes: A Systematic Review.
Jansen AML, Goel A
Clin Gastroenterol Hepatol 2020 Aug;18(9):1949-1960. Epub 2020 Mar 5 doi: 10.1016/j.cgh.2020.02.049. PMID: 32147591Free PMC Article
Risk of colorectal cancer with hysterectomy and oophorectomy: A systematic review and meta-analysis.
Luo G, Zhang Y, Wang L, Huang Y, Yu Q, Guo P, Li K
Int J Surg 2016 Oct;34:88-95. Epub 2016 Aug 26 doi: 10.1016/j.ijsu.2016.08.518. PMID: 27568653
Family history and the natural history of colorectal cancer: systematic review.
Henrikson NB, Webber EM, Goddard KA, Scrol A, Piper M, Williams MS, Zallen DT, Calonge N, Ganiats TG, Janssens AC, Zauber A, Lansdorp-Vogelaar I, van Ballegooijen M, Whitlock EP
Genet Med 2015 Sep;17(9):702-12. Epub 2015 Jan 15 doi: 10.1038/gim.2014.188. PMID: 25590981Free PMC Article
Iron and cancer risk--a systematic review and meta-analysis of the epidemiological evidence.
Fonseca-Nunes A, Jakszyn P, Agudo A
Cancer Epidemiol Biomarkers Prev 2014 Jan;23(1):12-31. Epub 2013 Nov 15 doi: 10.1158/1055-9965.EPI-13-0733. PMID: 24243555
Folate-genetics and colorectal neoplasia: what we know and need to know next.
Figueiredo JC, Levine AJ, Crott JW, Baurley J, Haile RW
Mol Nutr Food Res 2013 Apr;57(4):607-27. Epub 2013 Feb 8 doi: 10.1002/mnfr.201200278. PMID: 23401104

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    Clinical resources

    Practice guidelines

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    Curated

    • NICE, 2021
      UK NICE Guideline NG151, Colorectal cancer, 2021

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    Reviews

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