CTRCT19 is characterized by autosomal dominant or recessive cataract of various types, including pulverulent, late-onset cortical pulverulent, total, nuclear, membranous, lamellar, sutural, and posterior polar cataract. Other ocular features include nystagmus, amblyopia, and esotropia. Intrafamilial and intraindividual variability has been reported (Pras et al., 2002; Ponnam et al., 2008; Berry et al., 2020; Pei et al., 2020; Wang et al., 2021; Fernandez-Alcalde et al., 2021; Berry et al., 2022). [from OMIM]