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Schizophrenia 9(SCZD9)

MedGen UID:: 346728
•Concept ID:: C1858050
•: Mental or Behavioral Dysfunction

Synonyms:	SCHIZOPHRENIA 9, SUSCEPTIBILITY TO; SCHIZOPHRENIA SUSCEPTIBILITY LOCUS, CHROMOSOME 1q42-RELATED; SCZD9

Gene (location): Gene(s) directly associated with this condition or phenotype.	DISC1 (1q42.2)

Monarch Initiative:	MONDO:0011498
OMIM®:	604906

Definition

A schizophrenia that has material basis in a mutation of DISC1 on chromosome 1q42.2. [from MONDO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVSchizophrenia
- CROGVChromosome 2p16.3 deletion syndrome
- CROGVSchizophrenia 1
- CROGVSchizophrenia 2
- CROGVSchizophrenia 3
- CROGVSchizophrenia 4
- CROGVSchizophrenia 5
- CROGVSchizophrenia 6
- CROGVSchizophrenia 7
- CROGVSchizophrenia 8
- CROGVSchizophrenia 9
- CROGVSchizophrenia 10
- CROGVSchizophrenia 11
- CROGVSchizophrenia 12
- CROGVSchizophrenia 13
- CROGVSchizophrenia 14
- CROGVSchizophrenia 15
- CROGVSchizophrenia 16
- CROGVSchizophrenia 18
- CROGVSchizophrenia 19

Abnormality of the nervous system
- Abnormal nervous system physiology
  - Abnormality of mental function
    - Abnormal experience of reality
      - Abnormal psychotic pattern
        Schizophrenia
        Schizophrenia 9

Professional guidelines

PubMed

A preliminary analysis of association between the down-regulation of microRNA-181b expression and symptomatology improvement in schizophrenia patients before and after antipsychotic treatment.

Song HT, Sun XY, Zhang L, Zhao L, Guo ZM, Fan HM, Zhong AF, Niu W, Dai YH, Zhang LY, Shi Z, Liu XP, Lu J
J Psychiatr Res 2014 Jul;54:134-40. Epub 2014 Mar 20 doi: 10.1016/j.jpsychires.2014.03.008. PMID: 24694668

A retrospective chart review of risperidone use in treatment-resistant children and adolescents with psychiatric disorders.

Simeon J, Milin R, Walker S
Prog Neuropsychopharmacol Biol Psychiatry 2002 Feb;26(2):267-75. doi: 10.1016/s0278-5846(01)00264-0. PMID: 11817503

A follow-up study of early onset psychosis: comparison between outcome diagnoses of schizophrenia, mood disorders, and personality disorders.

McClellan JM, Werry JS, Ham M
J Autism Dev Disord 1993 Jun;23(2):243-62. doi: 10.1007/BF01046218. PMID: 8331046

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