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Fetal anticonvulsant syndrome

MedGen UID:
781143
Concept ID:
C1739111
Disease or Syndrome
Synonyms: FACS; fetal AEDS; Fetal AEDS; fetal anticonvulsant syndrome; Fetal antiepileptic drug syndrome; fetal antiepileptic drug syndrome; Fetus affected by placental transfer of anticonvulsant; Foetal anticonvulsant syndrome; Foetus affected by placental transfer of anticonvulsant
SNOMED CT: Fetus affected by placental transfer of anticonvulsant (429211000124107); Foetus affected by placental transfer of anticonvulsant (429211000124107); Fetal anticonvulsant syndrome (429211000124107); Foetal anticonvulsant syndrome (429211000124107)
 
Monarch Initiative: MONDO:0018262
Orphanet: ORPHA370068

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFetal anticonvulsant syndrome

Recent clinical studies

Etiology

Guven MA, Batukan C, Ceylaner S, Ceylaner G, Uzel M
J Matern Fetal Neonatal Med 2006 Feb;19(2):115-7. doi: 10.1080/14767050500420665. PMID: 16676441
Rasalam AD, Hailey H, Williams JH, Moore SJ, Turnpenny PD, Lloyd DJ, Dean JC
Dev Med Child Neurol 2005 Aug;47(8):551-5. doi: 10.1017/s0012162205001076. PMID: 16108456
Glover SJ, Quinn AG, Barter P, Hart J, Moore SJ, Dean JC, Turnpenny PD
Ophthalmology 2002 May;109(5):942-7. doi: 10.1016/s0161-6420(02)00959-4. PMID: 11986102
Dean JC, Moore SJ, Osborne A, Howe J, Turnpenny PD
Clin Genet 1999 Sep;56(3):216-20. doi: 10.1034/j.1399-0004.1999.560306.x. PMID: 10563481
Vorhees CV
J Pharmacol Exp Ther 1983 Nov;227(2):274-87. PMID: 6195326

Diagnosis

Jackson A, Ward H, Bromley RL, Deshpande C, Vasudevan P, Scurr I, Dean J, Shannon N, Berg J, Holder S, Baralle D, Clayton-Smith J; DDD Study.
Arch Dis Child 2020 Apr;105(4):384-389. Epub 2019 Sep 3 doi: 10.1136/archdischild-2018-316547. PMID: 31481360
Bromley RL, Baker GA, Clayton-Smith J, Wood AG
Neurotoxicol Teratol 2019 Jan - Feb;71:16-21. Epub 2018 Nov 16 doi: 10.1016/j.ntt.2018.11.003. PMID: 30453023
Mohd Yunos H, Green A
Ir J Med Sci 2018 Nov;187(4):965-968. Epub 2018 Feb 3 doi: 10.1007/s11845-018-1757-6. PMID: 29396778
Rasalam AD, Hailey H, Williams JH, Moore SJ, Turnpenny PD, Lloyd DJ, Dean JC
Dev Med Child Neurol 2005 Aug;47(8):551-5. doi: 10.1017/s0012162205001076. PMID: 16108456
Glover SJ, Quinn AG, Barter P, Hart J, Moore SJ, Dean JC, Turnpenny PD
Ophthalmology 2002 May;109(5):942-7. doi: 10.1016/s0161-6420(02)00959-4. PMID: 11986102

Therapy

Guven MA, Batukan C, Ceylaner S, Ceylaner G, Uzel M
J Matern Fetal Neonatal Med 2006 Feb;19(2):115-7. doi: 10.1080/14767050500420665. PMID: 16676441
Rasalam AD, Hailey H, Williams JH, Moore SJ, Turnpenny PD, Lloyd DJ, Dean JC
Dev Med Child Neurol 2005 Aug;47(8):551-5. doi: 10.1017/s0012162205001076. PMID: 16108456
Glover SJ, Quinn AG, Barter P, Hart J, Moore SJ, Dean JC, Turnpenny PD
Ophthalmology 2002 May;109(5):942-7. doi: 10.1016/s0161-6420(02)00959-4. PMID: 11986102
Dean JC, Moore SJ, Osborne A, Howe J, Turnpenny PD
Clin Genet 1999 Sep;56(3):216-20. doi: 10.1034/j.1399-0004.1999.560306.x. PMID: 10563481
Pearl KN, Dickens S, Latham P
Arch Dis Child 1984 Oct;59(10):989-90. doi: 10.1136/adc.59.10.989. PMID: 6497436Free PMC Article

Prognosis

Kinney MO, Morrow J, Patterson CC, Campbell E, Russell A, Smithson HW, Parsons L, Morrison PJ, Bromley R, Liggan B, Delanty N, Irwin B, Hunt SJ, Craig JJ
J Neurol Neurosurg Psychiatry 2018 Dec;89(12):1320-1323. Epub 2018 Apr 16 doi: 10.1136/jnnp-2017-317368. PMID: 29661925
Al Wattar BH, Tamilselvan K, Khan R, Kelso A, Sinha A, Pirie AM, McCorry D, Khan KS, Thangaratinam S; Antiepileptic Drug Management in Pregnancy (EMPIRE) Collaborative Network.
BJOG 2017 Mar;124(4):661-667. Epub 2016 Nov 16 doi: 10.1111/1471-0528.14430. PMID: 27860117

Clinical prediction guides

Bromley RL, Baker GA, Clayton-Smith J, Wood AG
Neurotoxicol Teratol 2019 Jan - Feb;71:16-21. Epub 2018 Nov 16 doi: 10.1016/j.ntt.2018.11.003. PMID: 30453023
Kinney MO, Morrow J, Patterson CC, Campbell E, Russell A, Smithson HW, Parsons L, Morrison PJ, Bromley R, Liggan B, Delanty N, Irwin B, Hunt SJ, Craig JJ
J Neurol Neurosurg Psychiatry 2018 Dec;89(12):1320-1323. Epub 2018 Apr 16 doi: 10.1136/jnnp-2017-317368. PMID: 29661925
Glover SJ, Quinn AG, Barter P, Hart J, Moore SJ, Dean JC, Turnpenny PD
Ophthalmology 2002 May;109(5):942-7. doi: 10.1016/s0161-6420(02)00959-4. PMID: 11986102

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