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Staphylococcal toxic-shock syndrome

MedGen UID:
811401
•Concept ID:
C3714602
•
Disease or Syndrome
Synonyms: Bacterial toxic-shock syndrome; Shock, Toxic
SNOMED CT: Staphylococcal toxic shock syndrome (240450004)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
•Concept ID:
CN307044
•
Finding
Source: Orphanet
clinical entity without genetic inheritance.
See: This record
Not genetically inherited (Orphanet)
 
Monarch Initiative: MONDO:0020545
Orphanet: ORPHA99919

Definition

Staphylococcal toxic shock syndrome (staphylococcal TSS) is an acute disease mediated by the production of superantigenic toxins, characterized by high fever, skin rash followed by skin peeling, hypotension, vomiting, diarrhea and potentially leading to multisystem organ failure and caused by a <i>Staphylococcus aureus</i> bacterial infection. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStaphylococcal toxic-shock syndrome

Professional guidelines

PubMed

Optimum treatment of staphylococcal infections.
Turnidge J, Grayson ML
Drugs 1993 Mar;45(3):353-66. doi: 10.2165/00003495-199345030-00004. PMID: 7682906

Recent clinical studies

Etiology

Searching the Staphylococcal Toxic Shock Syndrome Toxin -1 in Septic Children with negative Cultures: A Comparative Study in Tehran, Iran.
Noorbakhsh S, Rabiei AA, Rahbarimanesh AA, Haghighi M, Ashouri S
Infect Disord Drug Targets 2021;21(2):187-192. doi: 10.2174/1871526520666200731180641. PMID: 32735530
Clinical and Molecular Epidemiology of Staphylococcal Toxic Shock Syndrome in the United Kingdom.
Sharma H, Smith D, Turner CE, Game L, Pichon B, Hope R, Hill R, Kearns A, Sriskandan S
Emerg Infect Dis 2018 Feb;24(2):258-66. doi: 10.3201/eid2402.170606. PMID: 29350159Free PMC Article
Toxic shock syndrome.
Dass R, Nishad P, Singhi S
Indian J Pediatr 2004 May;71(5):433-5. doi: 10.1007/BF02725635. PMID: 15163875
Infectious exanthems and unusual infections.
Vincent JM, Demers DM, Bass JW
Adolesc Med 2000 Jun;11(2):327-58. PMID: 10916128
The toxic shock syndromes.
Stevens DL
Infect Dis Clin North Am 1996 Dec;10(4):727-46. doi: 10.1016/s0891-5520(05)70324-x. PMID: 8958166

Diagnosis

Staphylococcal toxic shock syndrome.
Barros Pinto MP
J Hematop 2023 Sep;16(3):189-190. Epub 2023 May 11 doi: 10.1007/s12308-023-00547-6. PMID: 38175396
Clinical and Molecular Epidemiology of Staphylococcal Toxic Shock Syndrome in the United Kingdom.
Sharma H, Smith D, Turner CE, Game L, Pichon B, Hope R, Hill R, Kearns A, Sriskandan S
Emerg Infect Dis 2018 Feb;24(2):258-66. doi: 10.3201/eid2402.170606. PMID: 29350159Free PMC Article
Toxic shock syndrome.
Dass R, Nishad P, Singhi S
Indian J Pediatr 2004 May;71(5):433-5. doi: 10.1007/BF02725635. PMID: 15163875
Staphylococcal toxic shock syndrome. Suspicion and prevention are keys to control.
Issa NC, Thompson RL
Postgrad Med 2001 Oct;110(4):55-6, 59-62. doi: 10.3810/pgm.2001.10.1045. PMID: 11675982
The toxic shock syndromes.
Stevens DL
Infect Dis Clin North Am 1996 Dec;10(4):727-46. doi: 10.1016/s0891-5520(05)70324-x. PMID: 8958166

Therapy

Toxic shock syndrome.
Dass R, Nishad P, Singhi S
Indian J Pediatr 2004 May;71(5):433-5. doi: 10.1007/BF02725635. PMID: 15163875
Toxic streptococcal syndrome.
Stanford DG, Georgouras KE, Konya J, Pang B
Australas J Dermatol 1997 Aug;38(3):158-60. doi: 10.1111/j.1440-0960.1997.tb01136.x. PMID: 9293666
The toxic shock syndromes.
Stevens DL
Infect Dis Clin North Am 1996 Dec;10(4):727-46. doi: 10.1016/s0891-5520(05)70324-x. PMID: 8958166
Optimum treatment of staphylococcal infections.
Turnidge J, Grayson ML
Drugs 1993 Mar;45(3):353-66. doi: 10.2165/00003495-199345030-00004. PMID: 7682906
Risk factors for staphylococcal toxic-shock syndrome.
Kehrberg MW, Latham RH, Haslam BT, Hightower A, Tanner M, Jacobson JA, Barbour AG, Noble V, Smith CB
Am J Epidemiol 1981 Dec;114(6):873-9. doi: 10.1093/oxfordjournals.aje.a113257. PMID: 7315834

Prognosis

COVID-19 and the clinical course of rheumatic manifestations.
Ahmed S, Zimba O, Gasparyan AY
Clin Rheumatol 2021 Jul;40(7):2611-2619. Epub 2021 Mar 17 doi: 10.1007/s10067-021-05691-x. PMID: 33733315Free PMC Article
Toxic shock syndrome.
Dass R, Nishad P, Singhi S
Indian J Pediatr 2004 May;71(5):433-5. doi: 10.1007/BF02725635. PMID: 15163875
Infectious exanthems and unusual infections.
Vincent JM, Demers DM, Bass JW
Adolesc Med 2000 Jun;11(2):327-58. PMID: 10916128
Streptococcal toxic shock-like syndrome. The importance of surgical intervention.
Wood TF, Potter MA, Jonasson O
Ann Surg 1993 Feb;217(2):109-14. doi: 10.1097/00000658-199302000-00003. PMID: 8439208Free PMC Article
Prolonged use of a diaphragm and toxic shock syndrome.
Baehler EA, Dillon WP, Cumbo TJ, Lee RV
Fertil Steril 1982 Aug;38(2):248-50. doi: 10.1016/s0015-0282(16)46467-8. PMID: 7106318

Clinical prediction guides

COVID-19 and the clinical course of rheumatic manifestations.
Ahmed S, Zimba O, Gasparyan AY
Clin Rheumatol 2021 Jul;40(7):2611-2619. Epub 2021 Mar 17 doi: 10.1007/s10067-021-05691-x. PMID: 33733315Free PMC Article
Staphylococcal toxic shock syndrome 2000-2006: epidemiology, clinical features, and molecular characteristics.
DeVries AS, Lesher L, Schlievert PM, Rogers T, Villaume LG, Danila R, Lynfield R
PLoS One 2011;6(8):e22997. Epub 2011 Aug 10 doi: 10.1371/journal.pone.0022997. PMID: 21860665Free PMC Article
Staphylococcal toxic-shock-syndrome-toxin-1 as a risk factor for disease relapse in Wegener's granulomatosis.
Popa ER, Stegeman CA, Abdulahad WH, van der Meer B, Arends J, Manson WM, Bos NA, Kallenberg CG, Tervaert JW
Rheumatology (Oxford) 2007 Jun;46(6):1029-33. Epub 2007 Apr 4 doi: 10.1093/rheumatology/kem022. PMID: 17409134
Lack of muco-cutaneous signs of toxic shock syndrome when T cells are absent: S. aureus shock in immunodeficient adults with multiple myeloma.
Kamel NS, Banks MC, Dosik A, Ursea D, Yarilina AA, Posnett DN
Clin Exp Immunol 2002 Apr;128(1):131-9. doi: 10.1046/j.1365-2249.2002.01805.x. PMID: 12033193Free PMC Article
Influence of surgery on in-vitro cytokine production by human monocytes.
Cabié A, Fitting C, Farkas JC, Laurian C, Cormier JM, Carlet J, Cavaillon JM
Cytokine 1992 Nov;4(6):576-80. doi: 10.1016/1043-4666(92)90022-j. PMID: 1292641

Recent systematic reviews

Systemic infections associated with tattoos or permanent makeup: A systematic review.
Rello J, Tejada S, Campogiani L, Adebanjo AG, Tammaro A
Med Clin (Barc) 2022 Feb 25;158(4):159-166. Epub 2021 Apr 24 doi: 10.1016/j.medcli.2021.01.014. PMID: 33902933

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