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Fibrosis

MedGen UID:
5179
Concept ID:
C0016059
Pathologic Function
Synonym: Fibroses
SNOMED CT: Fibrosis (112674009); Fibrous repair (112674009); Desmoplasia (112674009); Fibrous thickening (112674009); Fibroplasia (112674009); Fibrous replacement (112674009); Fibrosis (263756000)

Definition

The formation of fibrous tissue. [from NCI]

Recent clinical studies

Etiology

Morganstein T, Haidar Z, Trivlidis J, Azuelos I, Huang MJ, Eidelman DH, Baglole CJ
Int J Mol Sci 2021 Nov 30;22(23) doi: 10.3390/ijms222312955. PMID: 34884756Free PMC Article
Wu R, Li J, Tu G, Su Y, Zhang X, Luo Z, Rong R, Zhang Y
Front Immunol 2021;12:699192. Epub 2021 Oct 29 doi: 10.3389/fimmu.2021.699192. PMID: 34777334Free PMC Article
Hwang SH, Lee YM, Choi Y, Son HE, Ryu JY, Na KY, Chin HJ, Jeon NL, Kim S
Int J Mol Sci 2021 Oct 5;22(19) doi: 10.3390/ijms221910758. PMID: 34639099Free PMC Article
Wang Y, Wang Y, Xue K, Gao F, Li C, Fang H
Arch Biochem Biophys 2021 Oct 30;711:109021. Epub 2021 Aug 28 doi: 10.1016/j.abb.2021.109021. PMID: 34464591
Pulakazhi Venu VK, Alston L, Iftinca M, Tsai YC, Stephens M, Warriyar K V V, Rehal S, Hudson G, Szczepanski H, von der Weid PY, Altier C, Hirota SA
Am J Physiol Gastrointest Liver Physiol 2021 Sep 1;321(3):G280-G297. Epub 2021 Jul 21 doi: 10.1152/ajpgi.00338.2019. PMID: 34288735

Diagnosis

Kositamongkol C, Charernboon T, Chaisathaphol T, Washirasaksiri C, Auesomwang C, Sitasuwan T, Charatcharoenwitthaya P, Phisalprapa P
Medicine (Baltimore) 2021 Nov 5;100(44):e27640. doi: 10.1097/MD.0000000000027640. PMID: 34871234Free PMC Article
Wu R, Li J, Tu G, Su Y, Zhang X, Luo Z, Rong R, Zhang Y
Front Immunol 2021;12:699192. Epub 2021 Oct 29 doi: 10.3389/fimmu.2021.699192. PMID: 34777334Free PMC Article
Ting Soon GS, Wee A
Indian J Pathol Microbiol 2021 Jun;64(Supplement):S104-S111. doi: 10.4103/IJPM.IJPM_947_20. PMID: 34135151
Rubiś P, Dziewięcka E, Szymańska M, Banyś R, Urbańczyk-Zawadzka M, Krupiński M, Mielnik M, Wiśniowska-Śmiałek S, Karabinowska A, Podolec P, Winiarczyk M, Gliniak M, Kaciczak M, Robak J, Karapetyan A, Wypasek E
Cells 2021 May 23;10(6) doi: 10.3390/cells10061295. PMID: 34071085Free PMC Article
Panizo S, Martínez-Arias L, Alonso-Montes C, Cannata P, Martín-Carro B, Fernández-Martín JL, Naves-Díaz M, Carrillo-López N, Cannata-Andía JB
Int J Mol Sci 2021 Jan 2;22(1) doi: 10.3390/ijms22010408. PMID: 33401711Free PMC Article

Therapy

Guan XX, Rao DN, Liu YZ, Zhou Y, Yang HH
Int J Mol Sci 2021 Oct 3;22(19) doi: 10.3390/ijms221910714. PMID: 34639055Free PMC Article
Zhou F, Wu T, Wang W, Cheng W, Wan S, Tian H, Chen T, Sun J, Ren Y
Front Endocrinol (Lausanne) 2021;12:672557. Epub 2021 May 14 doi: 10.3389/fendo.2021.672557. PMID: 34054733Free PMC Article
Chen S, Zhou J, Wu X, Meng T, Wang B, Liu H, Wang T, Zhao X, Kong Y, Wu S, Ou X, Jia J, Sun Y, You H
Hepatol Int 2021 Jun;15(3):611-620. Epub 2021 Mar 7 doi: 10.1007/s12072-021-10162-1. PMID: 33677771
Rottner L, Heeger CH, Lemes C, Wohlmuth P, Maurer T, Reissmann B, Fink T, Mathew S, Ouyang F, Kuck KH, Metzner A, Rillig A
Int Heart J 2021 Jan 30;62(1):65-71. Epub 2021 Jan 16 doi: 10.1536/ihj.20-301. PMID: 33455982
Prados ME, García-Martín A, Unciti-Broceta JD, Palomares B, Collado JA, Minassi A, Calzado MA, Appendino G, Muñoz E
Acta Pharmacol Sin 2021 Jul;42(7):1124-1138. Epub 2020 Aug 18 doi: 10.1038/s41401-020-0497-0. PMID: 32811965Free PMC Article

Prognosis

Kositamongkol C, Charernboon T, Chaisathaphol T, Washirasaksiri C, Auesomwang C, Sitasuwan T, Charatcharoenwitthaya P, Phisalprapa P
Medicine (Baltimore) 2021 Nov 5;100(44):e27640. doi: 10.1097/MD.0000000000027640. PMID: 34871234Free PMC Article
Duan YR, Chen BP, Chen F, Yang SX, Zhu CY, Ma YL, Li Y, Shi J
J Cell Mol Med 2021 Jun;25(11):4922-4937. Epub 2021 May 3 doi: 10.1111/jcmm.16280. PMID: 33939247Free PMC Article
Fu H, Chu D, Geng X
Mol Cell Biochem 2021 Aug;476(8):3051-3064. Epub 2021 Apr 2 doi: 10.1007/s11010-021-04140-2. PMID: 33797702
Li N, Ouyang Y, Xu X, Yuan Z, Liu C, Zhu Z
J Cell Mol Med 2021 May;25(10):4765-4775. Epub 2021 Mar 26 doi: 10.1111/jcmm.16445. PMID: 33769664Free PMC Article
Mueller AC, Piper M, Goodspeed A, Bhuvane S, Williams JS, Bhatia S, Phan AV, Van Court B, Zolman KL, Peña B, Oweida AJ, Zakem S, Meguid C, Knitz MW, Darragh L, Bickett TE, Gadwa J, Mestroni L, Taylor MRG, Jordan KR, Dempsey P, Lucia MS, McCarter MD, Chiaro MD, Messersmith WA, Schulick RD, Goodman KA, Gough MJ, Greene CS, Costello JC, Neto AG, Lagares D, Hansen KC, Van Bokhoven A, Karam SD
Cancer Res 2021 Jun 15;81(12):3255-3269. Epub 2021 Feb 1 doi: 10.1158/0008-5472.CAN-20-3892. PMID: 33526513Free PMC Article

Clinical prediction guides

Mouchet N, Vu N, Turlin B, Rioux-Leclercq N, Jouneau S, Samson M, Amiot L
Int J Mol Sci 2021 Nov 19;22(22) doi: 10.3390/ijms222212490. PMID: 34830373Free PMC Article
Ting Soon GS, Wee A
Indian J Pathol Microbiol 2021 Jun;64(Supplement):S104-S111. doi: 10.4103/IJPM.IJPM_947_20. PMID: 34135151
Rubiś P, Dziewięcka E, Szymańska M, Banyś R, Urbańczyk-Zawadzka M, Krupiński M, Mielnik M, Wiśniowska-Śmiałek S, Karabinowska A, Podolec P, Winiarczyk M, Gliniak M, Kaciczak M, Robak J, Karapetyan A, Wypasek E
Cells 2021 May 23;10(6) doi: 10.3390/cells10061295. PMID: 34071085Free PMC Article
Fu H, Chu D, Geng X
Mol Cell Biochem 2021 Aug;476(8):3051-3064. Epub 2021 Apr 2 doi: 10.1007/s11010-021-04140-2. PMID: 33797702
Chen S, Zhou J, Wu X, Meng T, Wang B, Liu H, Wang T, Zhao X, Kong Y, Wu S, Ou X, Jia J, Sun Y, You H
Hepatol Int 2021 Jun;15(3):611-620. Epub 2021 Mar 7 doi: 10.1007/s12072-021-10162-1. PMID: 33677771

Recent systematic reviews

Zheng Q, Zou B, Wu Y, Yeo Y, Wu H, Stave CD, Cheung RC, Nguyen MH
Aliment Pharmacol Ther 2021 Nov;54(9):1100-1109. Epub 2021 Sep 1 doi: 10.1111/apt.16595. PMID: 34469587
Jia H, Ma T, Hao C
Life Sci 2020 Dec 1;262:118566. Epub 2020 Oct 8 doi: 10.1016/j.lfs.2020.118566. PMID: 33038373
Krastev TK, Schop SJ, Hommes J, Piatkowski A, van der Hulst RRWJ
J Plast Reconstr Aesthet Surg 2020 Nov;73(11):2033-2048. Epub 2020 Aug 20 doi: 10.1016/j.bjps.2020.08.023. PMID: 32948494
Lin Y, Li H, Jin C, Wang H, Jiang B
PLoS One 2020;15(1):e0227358. Epub 2020 Jan 15 doi: 10.1371/journal.pone.0227358. PMID: 31940395Free PMC Article
Bano A, Chaker L, Muka T, Mattace-Raso FUS, Bally L, Franco OH, Peeters RP, Razvi S
Thyroid 2020 Jun;30(6):806-820. Epub 2020 Feb 13 doi: 10.1089/thy.2019.0572. PMID: 31910097

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