Endoglin
A membrane glycoprotein and ANGIOGENESIS FACTOR that is expressed by cells of the VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; and MONOCYTES. It functions as a co-receptor for TRANSFORMING GROWTH FACTOR BETA and modulates CELL ADHESION. Mutations in the endoglin gene are associated with cases of HEREDITARY HEMORRHAGIC TELANGIECTASIA.
Year introduced: 2017
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Subheadings:
Tree Number(s): D12.776.543.750.250
MeSH Unique ID: D000071063
Entry Terms:
- CD105 Antigen
- Antigen, CD105
- Endoglin Protein
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