Cholesterol 24-Hydroxylase
A steroid hydroxylase that functions in CHOLESTEROL homeostasis in the brain. It converts cholesterol into 24S-hydroxycholesterol, which is transported over the BLOOD-BRAIN BARRIER more rapidly than unmetabolized cholesterol.
Year introduced: 2017 (1999)
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Subheadings:
Tree Number(s): D08.244.453.875.500, D08.244.453.915.025, D08.811.682.690.708.170.497.500, D08.811.682.690.708.170.915.025, D12.776.422.220.453.875.500, D12.776.422.220.453.915.025
MeSH Unique ID: D000072556
Registry Number: EC 1.14.14.25
Entry Terms:
- Cholesterol 24 Hydroxylase
- Brain-Specific 24S-Hydroxylase
- Brain Specific 24S Hydroxylase
- Cholestane Tetrol 24-Hydroxylase
- Cholestane Tetrol 24 Hydroxylase
- 5(beta)-cholestane-3 alpha,7 alpha,12 alpha,25-tetrol-24S-hydroxylase
- Cytochrome P450 46A1
- CYP46A1