Receptors, Enterotoxin
Guanylate cyclase-coupled receptors that bind bacterial ENTEROTOXINS, as well as the endogenous peptides guanylin and uroguanylin. Ligand binding stimulates production of CYCLIC GMP by EPITHELIAL CELLS of the intestinal lumen, altering barrier permeability and mucus secretion. Mutations in the gene (GUCY2C) encoding this receptor are associated with some cases of hereditary diarrhea (Diarrhea 6) and MECONIUM ILEUS.
Year introduced: 2018 (1981)
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Subheadings:
Tree Number(s): D08.811.520.650.600.500.250, D12.776.543.750.700.250, D12.776.543.750.750.330
MeSH Unique ID: D000074261
Registry Number: EC 4.6.1.2
Entry Terms:
- GC-C Receptor
- GC C Receptor
- Receptor, GC-C
- Enterotoxin Receptors
- Enterotoxin-Guanylin Receptor
- Enterotoxin Guanylin Receptor
- Receptor, Enterotoxin-Guanylin
- Guanyl Cyclase-C Receptor
- Guanyl Cyclase C Receptor
- Guanylin-Uroguanylin Receptor
- Guanylin Uroguanylin Receptor
- Receptor, Guanylin-Uroguanylin
- Guanylyl Cyclase C
- Cyclase C, Guanylyl
- Heat-Stable Enterotoxin Receptor
- Enterotoxin Receptor, Heat-Stable
- Heat Stable Enterotoxin Receptor
- Receptor, Heat-Stable Enterotoxin
- Receptor, Enterotoxin
- Receptor, Guanyl Cyclase-C
- Receptor, Guanyl Cyclase C
- Enterotoxin-Guanylin Receptors
- Enterotoxin Guanylin Receptors
- Receptors, Enterotoxin-Guanylin
- GC-C Receptors
- GC C Receptors
- Receptors, GC-C
- Guanyl Cyclase-C Receptors
- Cyclase-C Receptors, Guanyl
- Guanyl Cyclase C Receptors
- Guanylin-Uroguanylin Receptors
- Guanylin Uroguanylin Receptors
- Receptors, Guanylin-Uroguanylin
- Heat-Stable Enterotoxin Receptors
- Enterotoxin Receptors, Heat-Stable
- Heat Stable Enterotoxin Receptors
- Receptors, Heat-Stable Enterotoxin
- Receptors, Guanyl Cyclase-C
- Receptors, Guanyl Cyclase C
- Enterotoxin Receptor