Tolcapone
A benzophenone and nitrophenol compound that acts as an inhibitor of CATECHOL O-METHYLTRANSFERASE, an enzyme involved in the metabolism of DOPAMINE and LEVODOPA. It is used in the treatment of PARKINSON DISEASE in patients for whom levodopa is ineffective or contraindicated.
Year introduced: 2019 (1990)
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Subheadings:
Tree Number(s): D02.455.426.559.389.134.875, D02.455.426.559.389.657.566.845, D02.522.223.875, D02.640.743.845
MeSH Unique ID: D000077867
Registry Number: CIF6334OLY
Entry Terms:
- 3,4-Dihydroxy-5'-methyl-5-nitrobenzophenone
- 3,4 Dihydroxy 5' methyl 5 nitrobenzophenone
- SOM0226
- Ro 40-7592
- Ro 40 7592
- Ro 407592
- Ro-40-7592
- Ro407592
- Tasmar
Pharmacologic Action: