Pain Insensitivity, Congenital

A syndrome characterized by indifference to PAIN despite the ability to distinguish noxious from non-noxious stimuli. Absent corneal reflexes and INTELLECTUAL DISABILITY may be associated. Familial forms with autosomal recessive and autosomal dominant patterns of inheritance have been described. (Adams et al., Principles of Neurology, 6th ed, p1343)

Year introduced: 1996

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Tree Number(s): C10.668.829.700, C16.320.775

MeSH Unique ID: D000699

Entry Terms:

• Congenital Insensitivity To Pain
• Congenital Pain Indifference
• Congenital Pain Insensitivity
• Congenital Analgesia
• Insensitivity, Congenital Pain
• Pain Indifference, Congenital
• Congenital Pain Indifferences
• Analgesia, Congenital
• Channelopathy-Associated Insensitivity To Pain
• Congenital Indifference to Pain
• Insensitivity To Pain, Congenital

See Also:

• Hereditary Sensory and Autonomic Neuropathies
• Pain

All MeSH Categories
Diseases Category
Nervous System Diseases
Neuromuscular Diseases
Peripheral Nervous System Diseases
Pain Insensitivity, Congenital

All MeSH Categories
Diseases Category
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Genetic Diseases, Inborn
Pain Insensitivity, Congenital