Benserazide

An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.

Year introduced: 1991(1979)

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Tree Number(s): D02.442.175

MeSH Unique ID: D001545

Registry Number: 762OS3ZEJU

Entry Terms:

• Seryltrihydroxybenzylhydrazine
• Seryltrihydroxy Benzylhydrazine
• Benzylhydrazine, Seryltrihydroxy
• DL-Serine 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide
• Serazide
• Ro 4-4602
• Ro 4 4602
• Ro 44602

Previous Indexing:

• Benzene (1966-1967)
• Benzene Derivatives (1968-1971)
• Benzyl Compounds (1972)
• Hydrazines (1966-1972)
• Serine (1966-1972)

Pharmacologic Action:

• Antiparkinson Agents
• Enzyme Inhibitors
• Dopamine Agents

All MeSH Categories
Chemicals and Drugs Category
Organic Chemicals
Hydrazines
Benserazide