Mustard Compounds
Strong alkylating and immunosuppressive agents whose biological activity is based on the presence of bis(2-chloroethyl)- groups. Although otherwise structurally diverse, the compounds have in common the capacity to contribute alkyl groups to DNA. They are generally highly toxic but include among their number many widely used and effective antineoplastic agents.
Year introduced: 1968
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Subheadings:
Tree Number(s): D02.455.526.728
MeSH Unique ID: D009150
Entry Terms: