Supranuclear Palsy, Progressive
A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)
Year introduced: 1987
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Subheadings:
Tree Number(s): C10.228.140.079.882, C10.228.662.700, C10.292.562.750.500, C10.574.945.500, C10.597.622.447.690, C11.590.472.500, C23.888.592.636.447.690
MeSH Unique ID: D013494
Entry Terms:
- Progressive Supranuclear Palsies
- Supranuclear Palsies, Progressive
- Palsy, Progressive Supranuclear
- Progressive Supranuclear Palsy
- Richardson's Syndrome
- Richardson Syndrome
- Steele-Richardson-Olszewski Disease
- Steele Richardson Olszewski Disease
- Steele-Richardson-Olszewski Syndrome
- Steele Richardson Olszewski Syndrome
- Ophthalmoplegia, Progressive Supranuclear
- Supranuclear Ophthalmoplegia, Progressive
- Progressive Supranuclear Ophthalmoplegia
- Supranuclear Palsy, Progressive, 1
- Progressive Supranuclear Palsy 1
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