Monocrotaline
A pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. Significant attenuation of the cardiopulmonary changes are noted after oral magnesium treatment.
Year introduced: 1992
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Subheadings:
Tree Number(s): D03.132.716.500, D03.633.100.772.500
MeSH Unique ID: D016686
Registry Number: 73077K8HYV
Entry Terms:
- Monocrotaline Hydrochloride (13alpha,14alpha)-Isomer
- Monocrotaline, (all-xi)-Isomer
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