Aristolochic Acids

Nitro-phenanthrenes occurring in ARISTOLOCHIACEAE and other plants. They derive from stephanine (APORPHINES) by oxidative ring cleavage. The nitro group is a reactive alkylator (ALKYLATING AGENTS) that binds to biological macromolecules. Ingestion by humans is associated with nephropathy (NEPHRITIS). There is no relationship to the similar named aristolochene (SESQUITERPENES).

Year introduced: 2003

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Tree Number(s): D02.455.426.559.847.723.089, D02.640.139, D04.615.723.089

MeSH Unique ID: D034341

Previous Indexing:

• Phenanthrenes (1965-2002)

All MeSH Categories
Chemicals and Drugs Category
Organic Chemicals
Hydrocarbons
Hydrocarbons, Cyclic
Hydrocarbons, Aromatic
Polycyclic Aromatic Hydrocarbons
Phenanthrenes
Aristolochic Acids

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Chemicals and Drugs Category
Organic Chemicals
Nitro Compounds
Aristolochic Acids

All MeSH Categories
Chemicals and Drugs Category
Polycyclic Compounds
Polycyclic Aromatic Hydrocarbons
Phenanthrenes
Aristolochic Acids