Integrin alpha6beta4
This intrgrin is a key component of HEMIDESMOSOMES and is required for their formation and maintenance in epithelial cells. Integrin alpha6beta4 is also found on thymocytes, fibroblasts, and Schwann cells, where it functions as a laminin receptor (RECEPTORS, LAMININ) and is involved in wound healing, cell migration, and tumor invasiveness.
Year introduced: 2003
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Subheadings:
Tree Number(s): D12.776.543.750.705.408.460.170, D12.776.543.750.705.876.750
MeSH Unique ID: D039161
Entry Terms:
- alpha6beta4, Integrin
- alpha(6)beta(4) Integrin
- alpha6 beta4 Integrin
- Integrin, alpha6 beta4
- beta4 Integrin, alpha6
- Integrin alpha(6),beta(4)
- A9 Antigen
- Antigen, A9
- TSP-180
- Tumor Specific Protein-180 Complex
- Tumor Specific Protein 180 Complex
- alpha(6)beta(4) Epithelial Integrin
- Laminin-5 Receptor (alpha6beta4 Integrin)
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