Van der Woude syndrome [Supplementary Concept]
An autosomal dominant hereditary developmental disorder characterized by pits and/or sinuses of the lower lip, and cleft lip and/or cleft palate (CL/P, CP). It is the most common cleft syndrome. Mutations in the IRF6 gene have been identified. OMIM: 119300
Date introduced: August 25, 2010
MeSH Unique ID: C536528
Heading Mapped to:
Entry Terms:
- Lip-Pit Syndrome
- Lip pit syndrome
- Cleft lip and-or palate with mucous cysts of lower lip