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liver regeneration factor 1 [Supplementary Concept]
a leucine-zipper protein that is rapidly & highly induced in regenerating liver; MW 21 kDa; amino acid sequence given in first source
Date introduced: May 29, 1991
Activating Transcription Factor 3
An activating transcription factor that plays a key role in cellular responses to GENOTOXIC STRESS and OXIDATIVE STRESS.
Year introduced: 2006(1994)
Activating Transcription Factors
Activating transcription factors were originally identified as DNA-BINDING PROTEINS that interact with early promoters from ADENOVIRUSES. They are a family of basic leucine zipper transcription factors that bind to the consensus site TGACGTCA of the cyclic AMP response element, and are closely related to CYCLIC AMP-RESPONSIVE DNA-BINDING PROTEIN.
Year introduced: 2006
Basic-Leucine Zipper Transcription Factors
A large superfamily of transcription factors that contain a region rich in BASIC AMINO ACID residues followed by a LEUCINE ZIPPER domain.
Transcription Factors
Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.
Year introduced: 1977
Proteins
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.
Year introduced: /metabolism was PROTEIN METABOLISM 1963-1965
DNA-Binding Proteins
Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.
Year introduced: 1984
Amino Acids, Peptides, and Proteins
Amino acids and chains of amino acids connected by peptide linkages.
Year introduced: 1998