Sequence 3 from Patent EP2270230

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IGFBP5 is released by senescent cells and is internalized by healthy cells, promoting their senescence through interaction with retinoic receptors. [Cell Commun Signal. 2024]
IGFBP5 is released by senescent cells and is internalized by healthy cells, promoting their senescence through interaction with retinoic receptors.
Alessio N, Aprile D, Peluso G, Mazzone V, Patrone D, Di Bernardo G, Galderisi U. Cell Commun Signal. 2024 Feb 13; 22(1):122. Epub 2024 Feb 13.
Transcriptional profile of human thymus reveals IGFBP5 is correlated with age-related thymic involution. [Front Immunol. 2024]
Transcriptional profile of human thymus reveals IGFBP5 is correlated with age-related thymic involution.
Yang X, Chen X, Wang W, Qu S, Lai B, Zhang J, Chen J, Han C, Tian Y, Xiao Y, et al. Front Immunol. 2024; 15:1322214. Epub 2024 Jan 22.
Secreted insulin-like growth factor binding protein 5 functions as a tumor suppressor and chemosensitizer through inhibiting insulin-like growth factor 1 receptor/protein kinase B pathway in acute myeloid leukemia. [Neoplasia. 2024]
Secreted insulin-like growth factor binding protein 5 functions as a tumor suppressor and chemosensitizer through inhibiting insulin-like growth factor 1 receptor/protein kinase B pathway in acute myeloid leukemia.
Zhang B, Deng X, You R, Liu J, Hou D, Wang X, Chen S, Li D, Fu Q, Zhang J, et al. Neoplasia. 2024 Jan; 47:100952. Epub 2023 Dec 29.

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Nucleotide