PDZD8-deficient mice accumulate cholesteryl esters in the brain as a result of impaired lipophagy.
Morita K, Wada M, Nakatani K, Matsumoto Y, Hayashi N, Yamahata I, Mitsunari K, Mukae N, Takahashi M, Izumi Y, et al. iScience. 2022 Dec 22; 25(12):105612. Epub 2022 Nov 16.