Homo sapiens complement C1s (C1S), transcript variant 1, mRNA

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Cytoprotective effects of C1s enzyme in macrophages in atherosclerosis mediated through the LRP5 and Wnt/β-catenin pathway. [Mol Immunol. 2024]
Cytoprotective effects of C1s enzyme in macrophages in atherosclerosis mediated through the LRP5 and Wnt/β-catenin pathway.
Yuan D, Zheng Z, Shen C, Ye J, Zhu L. Mol Immunol. 2024 Feb; 166:29-38. Epub 2024 Jan 12.
A homozygous loss-of-function C1S mutation is associated with Kikuchi-Fujimoto disease. [Clin Immunol. 2023]
A homozygous loss-of-function C1S mutation is associated with Kikuchi-Fujimoto disease.
Alshekaili J, Nasr I, Al-Rawahi M, Ansari Z, Al Rahbi N, Al Balushi H, Al-Zadjali S, Al Kindi M, Al-Maawali A, Cook MC. Clin Immunol. 2023 Jul; 252:109646. Epub 2023 May 18.
Degradation of collagen I by activated C1s in periodontal Ehlers-Danlos Syndrome. [Front Immunol. 2023]
Degradation of collagen I by activated C1s in periodontal Ehlers-Danlos Syndrome.
Amberger A, Pertoll J, Traunfellner P, Kapferer-Seebacher I, Stoiber H, Klimaschewski L, Thielens N, Gaboriaud C, Zschocke J. Front Immunol. 2023; 14:1157421. Epub 2023 Mar 7.

RefSeq alternative splicing
See 4 reference mRNA sequence splice variants for the C1S gene.
RefSeq protein product
See the reference protein sequence for complement C1s subcomponent isoform 1 preproprotein (NP_958850.1).

Protein
Protein sequence from Nucleotide coding region
PubMed
PubMed articles cited by Nucleotide sequence record
Taxonomy
Taxonomy sequences associated with Nucleotide record
Annotated Genomic
Genomic sequence records that have the current RNA records as annotated features marking the exons of genes.
BioSystems
BioSystems
CCDS
Link to Consensus CDS
Components (Core)
Links to Core components
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Functional Class
Functional class of the sequence domain architecture
Gene
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PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
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Ensembl [Ensembl]
Ensembl
GenScript latest version of gene cDNA ORF Clone [GenScript latest version of g...]
GenScript latest version of gene cDNA ORF Clone
complement C1s [Guide to Pharmacology]
complement C1s
Guide to Pharmacology
Order TALEN/CRISPR clone [GeneCopoeia Inc.]
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UCSC Genome Browser [UCSC Genome Browser]
UCSC Genome Browser
Order C1S cDNA clone/Protein/Antibody/RNAi [OriGene]
Order C1S cDNA clone/Protein/Antibody/RNAi
OriGene

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Nucleotide