H.sapiens RR2 mRNA for small subunit ribonucleotide reductase

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A comprehensive analysis of ribonucleotide reductase subunit M2 for carcinogenesis in pan-cancer. [PLoS One. 2024]
A comprehensive analysis of ribonucleotide reductase subunit M2 for carcinogenesis in pan-cancer.
Wang Y, Chen R, Zhang J, Zeng P. PLoS One. 2024; 19(4):e0299949. Epub 2024 Apr 18.
Targeting of RRM2 suppresses DNA damage response and activates apoptosis in atypical teratoid rhabdoid tumor. [J Exp Clin Cancer Res. 2023]
Targeting of RRM2 suppresses DNA damage response and activates apoptosis in atypical teratoid rhabdoid tumor.
Giang LH, Wu KS, Lee WC, Chu SS, Do AD, Changou CA, Tran HM, Hsieh TH, Chen HH, Hsieh CL, et al. J Exp Clin Cancer Res. 2023 Dec 20; 42(1):346. Epub 2023 Dec 20.
E2F8 exerts cancer-promoting effects by transcriptionally activating RRM2 and E2F8 knockdown synergizes with WEE1 inhibition in suppressing lung adenocarcinoma. [Biochem Pharmacol. 2023]
E2F8 exerts cancer-promoting effects by transcriptionally activating RRM2 and E2F8 knockdown synergizes with WEE1 inhibition in suppressing lung adenocarcinoma.
Liu K, Wang L, Lou Z, Guo L, Xu Y, Qi H, Fang Z, Mei L, Chen X, Zhang X, et al. Biochem Pharmacol. 2023 Dec; 218:115854. Epub 2023 Oct 19.

RefSeq alternative splicing
See 2 reference mRNA sequence splice variants for the RRM2 gene.

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Nucleotide