Entry - *300762 - MELANOMA ANTIGEN, FAMILY B, 16; MAGEB16 - OMIM

 
 
* 300762

MELANOMA ANTIGEN, FAMILY B, 16; MAGEB16


HGNC Approved Gene Symbol: MAGEB16

Cytogenetic location: Xp21.1     Genomic coordinates (GRCh38): X:35,798,342-35,803,772 (from NCBI)


TEXT

▼ Cloning and Expression

By searching databases for sequences similar to MAGED2 (300470), Chomez et al. (2001) identified MAGEB16. The deduced protein contains the characteristic MAGE domain of about 200 amino acids. RT-PCR detected MAGEB16 expression in testis, but not in other normal tissues examined.


▼ Mapping

By genomic sequence analysis, Chomez et al. (2001) mapped the MAGEB gene cluster to chromosome Xp22.2-p21.2.


▼ REFERENCES

  1. Chomez, P., De Backer, O., Bertrand, M., De Plaen, E., Boon, T., Lucas, S. An overview of the MAGE gene family with the identification of all human members of the family. Cancer Res. 61: 5544-5551, 2001. [PubMed: 11454705, related citations] [Full Text]


Creation Date:
Patricia A. Hartz : 3/5/2009
Edit History:
mgross : 03/05/2009

* 300762

MELANOMA ANTIGEN, FAMILY B, 16; MAGEB16


HGNC Approved Gene Symbol: MAGEB16

Cytogenetic location: Xp21.1     Genomic coordinates (GRCh38): X:35,798,342-35,803,772 (from NCBI)


TEXT

Cloning and Expression

By searching databases for sequences similar to MAGED2 (300470), Chomez et al. (2001) identified MAGEB16. The deduced protein contains the characteristic MAGE domain of about 200 amino acids. RT-PCR detected MAGEB16 expression in testis, but not in other normal tissues examined.


Mapping

By genomic sequence analysis, Chomez et al. (2001) mapped the MAGEB gene cluster to chromosome Xp22.2-p21.2.


REFERENCES

  1. Chomez, P., De Backer, O., Bertrand, M., De Plaen, E., Boon, T., Lucas, S. An overview of the MAGE gene family with the identification of all human members of the family. Cancer Res. 61: 5544-5551, 2001. [PubMed: 11454705] [Full Text: http://cancerres.aacrjournals.org/cgi/pmidlookup?view=long&pmid=11454705]


Creation Date:
Patricia A. Hartz : 3/5/2009

Edit History:
mgross : 03/05/2009



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: April 19, 2024