Alternative titles; symbols
HGNC Approved Gene Symbol: ABHD3
Cytogenetic location: 18q11.2 Genomic coordinates (GRCh38): 18:21,650,901-21,704,774 (from NCBI)
Edgar and Polak (2002) cloned mouse Abhd3, which they called Labh3. The deduced 411-amino acid protein has a central core predicted to form alpha/beta hydrolase folds and has a ser-ala-his catalytic triad characteristic of peroxidases. By database analysis, the authors identified human ABHD3, which encodes a deduced 409-amino acid protein that shares 93% amino acid identity with mouse Abhd3. Real-time PCR detected Abhd3 in most adult mouse tissues examined, with highest expression in liver. Abhd3 was also expressed at all embryonic stages examined.
Edgar (2003) stated that the ABHD3 gene mapped to chromosome 18q11.1.
Edgar, A. J., Polak, J. M. Cloning and tissue distribution of three murine alpha/beta hydrolase fold protein cDNAs. Biochem. Biophys. Res. Commun. 292: 617-625, 2002. [PubMed: 11922611] [Full Text: https://doi.org/10.1006/bbrc.2002.6692]
Edgar, A. J. The gene structure and expression of human ABHD1: overlapping polyadenylation signal sequence with Sec12. BMC Genomics 4: 18, 2003. Note: Electronic Article. [PubMed: 12735795] [Full Text: https://doi.org/10.1186/1471-2164-4-18]