Entry - *615046 - HISTONE GENE CLUSTER 3, H2B HISTONE FAMILY, MEMBER B; HIST3H2BB - OMIM

 
 
* 615046

HISTONE GENE CLUSTER 3, H2B HISTONE FAMILY, MEMBER B; HIST3H2BB


Alternative titles; symbols

HISTONE GENE CLUSTER 3, H2BB
HIST3 CLUSTER, H2BB


HGNC Approved Gene Symbol: H2BC26

Cytogenetic location: 1q42.13     Genomic coordinates (GRCh38): 1:228,458,103-228,458,558 (from NCBI)


▼ TEXT

For background information on histones, histone gene clusters, and the H2B histone family, see HIST1H2BA (609904).

▼ Cloning and Expression

By genomic sequence analysis, Marzluff et al. (2002) identified the mouse and human HIST3H2BB genes.


▼ Mapping

By genomic sequence analysis, Marzluff et al. (2002) determined that the histone gene cluster on chromosome 1q42, which they called histone gene cluster-3 (HIST3), contains 3 histone genes, including HIST3H2BB. The HIST3 cluster also contains an H2B pseudogene, HIST3H2BA.


▼ Gene Function

See HIST1H2BA (609904) for functional information on H2B histones.

▼ REFERENCES

  1. Marzluff, W. F., Gongidi, P., Woods, K. R., Jin, J., Maltais, L. J. The human and mouse replication-dependent histone genes. Genomics 80: 487-498, 2002. [PubMed: 12408966, related citations]


Creation Date:
Matthew B. Gross : 1/29/2013
Edit History:
mgross : 01/29/2013

* 615046

HISTONE GENE CLUSTER 3, H2B HISTONE FAMILY, MEMBER B; HIST3H2BB


Alternative titles; symbols

HISTONE GENE CLUSTER 3, H2BB
HIST3 CLUSTER, H2BB


HGNC Approved Gene Symbol: H2BC26

Cytogenetic location: 1q42.13     Genomic coordinates (GRCh38): 1:228,458,103-228,458,558 (from NCBI)


TEXT

For background information on histones, histone gene clusters, and the H2B histone family, see HIST1H2BA (609904).

Cloning and Expression

By genomic sequence analysis, Marzluff et al. (2002) identified the mouse and human HIST3H2BB genes.


Mapping

By genomic sequence analysis, Marzluff et al. (2002) determined that the histone gene cluster on chromosome 1q42, which they called histone gene cluster-3 (HIST3), contains 3 histone genes, including HIST3H2BB. The HIST3 cluster also contains an H2B pseudogene, HIST3H2BA.


Gene Function

See HIST1H2BA (609904) for functional information on H2B histones.

REFERENCES

  1. Marzluff, W. F., Gongidi, P., Woods, K. R., Jin, J., Maltais, L. J. The human and mouse replication-dependent histone genes. Genomics 80: 487-498, 2002. [PubMed: 12408966]


Creation Date:
Matthew B. Gross : 1/29/2013

Edit History:
mgross : 01/29/2013



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: April 16, 2024