txid11676[Organism:noexp] - PubChem BioAssay - NCBI

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Select item 17954461.

MT4 Cell Antiviral Assay from US Patent US10064873: "Compounds and compositions for treating HIV with derivatives of Betulin"

Source:: BindingDB

Protein Targets:: Envelope glycoprotein gp160 ; ...
Total:: 1

Assay data:74 Active, 5 Activity ≤ 1 nM, 74 Activity ≤ 1 µM, 74 Tested

AID:: 1795446

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19189222.

Anti-HIV activity against HIV-1 NL4-3 Nanoluc-sec virus infected in human MT4 cells assessed as viral growth inhibition by measuring luciferase activity measured after 3 days post-infection by Nano-Glo luciferase assay

Source:: ChEMBL

Assay data:13 Active, 1 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 13 Tested

AID:: 1918922

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19171083.

Antiviral activity against NNRTI resistant HIV1 LAI infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect measured after 5 days by MTT assay

Source:: ChEMBL

Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1917108

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19171054.

Antiviral activity against NNRTI resistant HIV1 harboring Gly190Ala mutant infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect measured after 5 days by MTT assay

Source:: ChEMBL

Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1917105

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19171045.

Antiviral activity against NNRTI resistant HIV1 harboring Tyr188Leu mutant infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect measured after 5 days by MTT assay

Source:: ChEMBL

Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1917104

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19171036.

Antiviral activity against NNRTI resistant HIV1 harboring Tyr181Cys mutant infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect measured after 5 days by MTT assay

Source:: ChEMBL

Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1917103

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19171027.

Antiviral activity against NNRTI resistant HIV1 harboring Val106Ala mutant infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect measured after 5 days by MTT assay

Source:: ChEMBL

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1917102

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19171018.

Antiviral activity against NNRTI resistant HIV1 harboring Lys103Asn mutant infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect measured after 5 days by MTT assay

Source:: ChEMBL

Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1917101

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19171009.

Antiviral activity against NNRTI resistant HIV1 harboring Leu100IIe mutant infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect measured after 5 days by MTT assay

Source:: ChEMBL

Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1917100

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 191709910.

Antiviral activity against wild type HIV1 IIIB assessed as viral growth inhibition measured after 5 days by MTT assay

Source:: ChEMBL

Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1917099

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 191693711.

Antiviral activity against HIV-1 NL4-3 infected in PBMC (unknown origin) assessed as reduction in viral replication

Source:: ChEMBL

Assay data:1 Active, 1 Tested

AID:: 1916937

Summary Compounds, Active PubMed Citation

Select item 191693512.

Antiviral activity against HIV-1 NL4-3 infected in human H9 cells assessed as reduction in viral replication at MOI of 0.03 measured after 48 hrs by Bright-Glo Luciferase Assay

Source:: ChEMBL

Assay data:1 Active, 1 Tested

AID:: 1916935

Summary Compounds, Active PubMed Citation

Select item 191693313.

Antiviral activity against recombinant HIV-1 infected in CD4+ human HeLa cells assessed as reduction in viral replication

Source:: ChEMBL

Assay data:3 Active, 3 Tested

AID:: 1916933

Summary Compounds, Active PubMed Citation

Select item 191605314.

Potency index, ratio of D-alaninyl analog EC50 to test compound EC50 for antiviral activity against HIV-1 IIIb infected in human MT2 cells

Source:: ChEMBL

Assay data:1 Tested

AID:: 1916053

Summary PubMed Citation

Select item 191605115.

Antiviral activity against HIV-1 IIIb infected in human MT2 cells assessed as reduction in virus induced cytopathic effect and measured after 5 days by XTT assay

Source:: ChEMBL

Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested

AID:: 1916051

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 191567016.

Antiviral activity against HIV-1 assessed as viral growth inhibition

Source:: ChEMBL

Assay data:1 Tested

AID:: 1915670

Summary PubMed Citation

Select item 191058317.

Inhibition of Influenza A virus (A/Wisconsin/09/2013(HIN1)) recombinant Neuraminidase using MUNANA as substrate incubated for 60 mins by fluorescence based assay

Source:: ChEMBL

Protein Target:: Integrase

Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1910583

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 190936018.

Antiviral activity against HIV-1 IIIB infected in human MT4 cells assessed as inhibition of viral replication measured after 5 days by Celltiter-Glo assay

Source:: ChEMBL

Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested

AID:: 1909360

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 190789819.

Antiviral activity against HIV-1 IIIB infected in human MT4 cells assessed as inhibition of virus-induced cell death preincubated for 1 hr with compound followed by viral infection measured after 5 days by MTT assay

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 3 Tested

AID:: 1907898

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 190789720.

Inhibition of wild type HIV1 protease expressed in Escherichia coli BL21 DE3 assessed as cleavage of fluorogenic substrate using EDANS-RESGIFLETSKR-DABCYL preincubated for 15 mins with compound followed by substrate addition and measured after 60 mins by microplate reader analysis

Source:: ChEMBL

Protein Target:: Protease

Assay data:3 Active, 2 Activity ≤ 1 µM, 7 Tested

AID:: 1907897

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Activity (IC50, etc) ≤ 1 nM (1,347)
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