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The drug is tested on Subdoligranulum variabile strain: DSM15176 for biotransformation. The drug concentrations were measured before and after a 12-h incubation by liquid-chromatography-coupled mass spectrometry (LC?MS)
Assay data:189 Tested
Summary
The drug is tested on Eubacterium ventriosum strain: ATCC27560 for biotransformation. The drug concentrations were measured before and after a 12-h incubation by liquid-chromatography-coupled mass spectrometry (LC?MS)
Assay data:244 Tested
The drug is tested on Clostridium sporogenes strain: ATCC15579 for biotransformation. The drug concentrations were measured before and after a 12-h incubation by liquid-chromatography-coupled mass spectrometry (LC?MS)
Assay data:217 Tested
The drug is tested on Clostridium sp. strain: fecal isolate for biotransformation. The drug concentrations were measured before and after a 12-h incubation by liquid-chromatography-coupled mass spectrometry (LC?MS)
Assay data:212 Tested
The drug is tested on Anaerotruncus colihominis strain: DSM17241 for biotransformation. The drug concentrations were measured before and after a 12-h incubation by liquid-chromatography-coupled mass spectrometry (LC?MS)
Assay data:245 Tested
The drug is tested on Bacteroides pectinophilus strain: ATCC43243 for biotransformation. The drug concentrations were measured before and after a 12-h incubation by liquid-chromatography-coupled mass spectrometry (LC?MS)
Assay data:242 Tested
Antibacterial activity against Clostridium tetani MTCC 449 assessed as bacterial growth inhibition by broth microdilution method
Assay data:5 Tested
Antibacterial activity against Clostridium septicum
Assay data:1 Tested
Inhibition of Botulinum neurotoxins/F
Assay data:2 Tested
Inhibition of Botulinum neurotoxins/A
Assay data:1 Active, 1 Tested
SummaryRelated BioAssays by Target
Inhibition of Botulinum neurotoxins/A LC at 20 uM relative to control
Inhibition of Botulinum neurotoxins/A LC at 200 uM relative to control
Reversible inhibition of Clostridium histolyticum collagenase unit of ColG at 7.5 uM using quenched fluorescent FSI-1 as substrate incubated for 2 min by rapid dilution assay
Assay data:4 Active, 4 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Reversible inhibition of Clostridium histolyticum peptidase domain of ColH at 1.25 uM using quenched fluorescent FSI-1 as substrate incubated for 2 min by rapid dilution assay
Inhibition of Clostridium histolyticum peptidase unit of CoLH at 100 uM relative to contol
Assay data:6 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Clostridium histolyticum collagenase unit of ColG assessed as inhibition constant incubated for 144 seconds by FRET based assay
Inhibition of Clostridium histolyticum peptidase unit of CoLH at 100 uM relative to control
Inhibition of Clostridium histolyticum collagenase unit of CoLH at 100 uM relative to control
Inhibition of Clostridium histolyticum CoLH at 100 uM relative to control
Inhibition of Clostridium histolyticum CoLH
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
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