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Biochemical Rat MASP2 Assay from US Patent US20240010684: "MASP INHIBITORY COMPOUNDS AND USES THEREOF"
Assay data:20 Active, 20 Activity ≤ 1 µM, 20 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
Biochemical Rat MASP1 Assay from US Patent US20240010684: "MASP INHIBITORY COMPOUNDS AND USES THEREOF"
Assay data:21 Active, 21 Activity ≤ 1 µM, 21 Tested
Biological and Stability Data from US Patent US11458151: "Toll-like receptor ligands"
Assay data:8 Active, 5 Activity ≤ 1 nM, 8 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Radioligand Binding Assay on Rat TAAR1 from US Patent US11697636: "Substituted benzamides"
Assay data:313 Active, 31 Activity ≤ 1 nM, 305 Activity ≤ 1 µM, 314 Tested
Radioligand Binding Assay on Mouse TAAR1 from US Patent US11697636: "Substituted benzamides"
Assay data:298 Active, 20 Activity ≤ 1 nM, 279 Activity ≤ 1 µM, 300 Tested
Competitive Radioligand Binding Assay from US Patent US11691947: "Isoindoline compositions and methods for treating neurodegenerative disease"
Assay data:81 Active, 3 Activity ≤ 1 nM, 79 Activity ≤ 1 µM, 93 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Binding to Nicotinic Receptor Subtypes from US Patent US11667638: "4-substitued cytisine analogues"
Assay data:50 Active, 3 Activity ≤ 1 nM, 50 Activity ≤ 1 µM, 50 Tested
Enzymatic Assay for MASP-2 from US Patent US11584714: "MASP-2 inhibitors and methods of use"
Assay data:436 Active, 324 Activity ≤ 1 µM, 479 Tested
Steroid Inhibition of TBPS Binding from US Patent US11542297: "Compositions and methods for treating CNS disorders"
Assay data:214 Active, 230 Activity ≤ 1 µM, 230 Tested
Radioligand Competition Binding Assay from US Patent US11518754: "Radiolabeled pharmaceuticals and methods of making and using same"
Assay data:10 Active, 2 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 10 Tested
Biological Assay (RFMS) from US Patent US11198681: "Heteroaryl inhibitors of PAD4"
Assay data:43 Active, 11 Activity ≤ 1 µM, 80 Tested
Steroid Inhibition of TBPS Binding from US Patent US11147877: "Compositions and methods for treating CNS disorders"
Assay data:11 Active, 17 Activity ≤ 1 µM, 17 Tested
Receptor [35S] GTPgammaS Binding Assays: (S1P1 GTPgammaS/S1P3 GTPgammaS) from US Patent US11058696: "Substituted bicyclic compounds"
Assay data:12 Active, 1 Activity ≤ 1 nM, 12 Activity ≤ 1 µM, 12 Tested
S1P1 Binding Assay from US Patent US11058696: "Substituted bicyclic compounds"
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
STING SPA Binding Assay from US Patent US11021511: "Cyclic dinucleotides as sting agonists"
Assay data:5 Active, 5 Activity ≤ 1 µM, 6 Tested
Rat FAAH Inhibition Assay from US Patent US10918640: "Azetidine derivatives"
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
FLIPR and cAMP Inhibition Assay from US Patent US10858365: "Triazolo-pyrimidine compounds and uses thereof"
Assay data:117 Active, 13 Activity ≤ 1 nM, 116 Activity ≤ 1 µM, 119 Tested
Enzymatic Activity Assay of MetAP2 from US Patent US10807971: "Pyrrolidinone compounds"
Assay data:17 Active, 17 Activity ≤ 1 µM, 17 Tested
Enzymatic Activity Assay of DPP-4 from US Patent US10807971: "Pyrrolidinone compounds"
Assay data:17 Active, 3 Activity ≤ 1 nM, 17 Activity ≤ 1 µM, 17 Tested
Enzyme Inhibition Assay from US Patent US10759791: "Mammalian and bacterial nitric oxide synthase inhibitors"
Assay data:24 Active, 21 Activity ≤ 1 µM, 24 Tested
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