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The compound was evaluated for its relative binding affinity against wild type scytalone dehydratase (SD);Relative Ki
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
The compound was evaluated for its relative binding affinity against mutant Y50F scytalone dehydratase; Relative Ki
The compound was evaluated for its relative binding affinity against mutant Y30F scytalone dehydratase; Relative Ki
The compound was evaluated for its relative binding affinity against mutant N131A scytalone dehydratase; Relative Ki
The compound was evaluated for its relative binding affinity against mutant H85N scytalone dehydratase; Relative Ki
The compound was evaluated for its relative binding affinity against mutant H110N scytalone dehydratase; Relative Ki
Inhibition of Magnaporthe grisea scytalone dehydratase
Assay data:27 Active, 19 Activity ≤ 1 nM, 27 Activity ≤ 1 µM, 27 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of Magnaporthe grisea Guy 11 isocitrate lyase
Assay data:4 Tested
Compound was evaluated for its inhibition constant against scytalone dehydratase (SD)
Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
The inhibitory activity (Ki) of the protonated compound was measured against scytalone dehydratase at pH 7.0
Assay data:3 Active, 1 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
The inhibitory activity (Ki) of the deprotonated compound was measured against scytalone dehydratase at pH 9.8
Assay data:3 Active, 2 Activity ≤ 1 µM, 4 Tested
The compound was evaluated for its binding affinity against wild type scytalone dehydratase (SD)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
The compound was evaluated for its binding affinity against mutant Y50F scytalone dehydratase
The compound was evaluated for its binding affinity against mutant Y30F scytalone dehydratase
The compound was evaluated for its binding affinity against mutant H85N scytalone dehydratase
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
The compound was evaluated for its binding affinity against mutant H110N scytalone dehydratase
Inhibition of scytalone dehydratase purified from Magnaporthe grisea
Assay data:19 Active, 17 Activity ≤ 1 nM, 19 Activity ≤ 1 µM, 19 Tested
Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe grisea
Assay data:29 Active, 18 Activity ≤ 1 nM, 29 Activity ≤ 1 µM, 29 Tested
Inhibitory activity against Scytalone dehydratase
Assay data:5 Active, 3 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested
Compound was evaluated for binding affinity towards SD (Scytalone dehydratase) against the rice pathogen Magnaporthe grisea
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
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