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Antiviral activity against Adenovirus type 5 VR-1523 infected in human Hep2 cells assessed as inhibition of virus-induced plaque formation/cytopathogenicity
Assay data:9 Tested
SummaryPubMed Citation
Antiviral activity against Human adenovirus 5 Adenoid 75 infected in A549 cells assessed as reduction in virus titer preincubated for 24 hrs followed by viral infection and measured after 72 hrs by microscopic analysis
Assay data:39 Tested
Antiviral activity against Human adenovirus 5 Adenoid 75 infected in A549 cells assessed as inhibition of viral adsorption at early stage of replication treated for 1 hr during viral infection followed by replacement with fresh medium and measured after 72 hrs by MTT assay
Assay data:42 Tested
Antiviral activity against Human adenovirus 5 infected in human A549 cells
Assay data:2 Tested
Antiviral activity against wild-type Human adenovirus 5 infected in human A549 cells assessed as inhibition of virus entry incubated for 48 hrs by fluorescence assay
Assay data:2 Active, 9 Tested
SummaryCompounds, ActivePubMed Citation
Antiviral activity against GFP-fused Human adenovirus 5 infected in 293beta5 cells assessed as inhibition of plaque formation incubated for 7 days by GFP reporter gene assay
Assay data:54 Active, 17 Activity ≤ 1 µM, 68 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antiviral activity against Human adenovirus 5 infected in human A549 cells assessed as inhibition of viral entry after 48 hrs by GFP reporter gene based assay
Assay data:9 Active, 1 Activity ≤ 1 µM, 10 Tested
Antiviral activity against Human adenovirus 5 infected in 293beta5 cells assessed as inhibition of plaque formation incubated for 7 days by GFP reporter gene assay
Assay data:41 Active, 19 Activity ≤ 1 µM, 55 Tested
Antiviral activity against Human adenovirus 5 infected in HEK293beta5 cells coexpressing GFP assessed as inhibition of plaque formation incubated for 7 days
Assay data:18 Active, 2 Activity ≤ 1 µM, 19 Tested
Antiviral activity against HAdV5 infected in 293beta5 cells assessed as inhibition of plaque formation after 7 days by GFP reporter gene assay
Assay data:6 Active, 6 Tested
Antiviral activity against HAdV5 infected in human A549 cells assessed as inhibition of viral entry preincubated for 45 mins followed by cell addition measured after 48 hrs by GFP reporter gene assay
Antiviral activity against human adenovirus 5 infected in HEK293 cells assessed as reduction in viral induced cytopathogenicity incubated for 5 days by Celltiter-Glo luminescent cell viability assay
Assay data:5 Active, 5 Tested
Inhibition of human adenovirus serotype 5 adenain protease expressed in Escherichia coli DL21 (DE3) using Ac-WLRGG*ARC(PT14)-NH2 as substrate by FLT assay
Assay data:15 Active, 15 Activity ≤ 1 µM, 16 Tested
Assay data:3 Active, 6 Tested
Assay data:11 Active, 4 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 11 Tested
Virucidal activity against Adenovirus 5 ATCC VR-1516 infected in human A549 cells assessed as viral cytopathic effect at pH 4 incubated for 1 hr measured after 6 days by three-fold serial dilution assay
Assay data:9 Active, 17 Tested
Virucidal activity against Adenovirus 5 ATCC VR-1516 infected in human A549 cells assessed as viral cytopathic effect at pH 7 incubated for 1 hr measured after 6 days by three-fold serial dilution assay
Assay data:2 Active, 17 Tested
Antiviral activity against Adenovirus type 5 F2853-5b infected in human A549 cells assessed as inhibition of viral replication after 24 hrs by RT-PCR analysis
Assay data:6 Active, 2 Activity ≤ 1 µM, 7 Tested
Antiviral activity against Human adenovirus type 5 infected in human A549 cells assessed as inhibition of viral replication by QPCR after 24 hrs
Assay data:1 Active, 1 Tested
Antiviral activity against Human adenovirus type 5 F2853-5b infected in A549 cells assessed as inhibition of DNA replication by QPCR assay
Assay data:1 Active, 2 Tested
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