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Antiparasitic activity against Ancylostoma caninum isolate PR assessed as compound concentration required to inhibit parasitic contraction by larval motility assay
Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antiparasitic activity against Ancylostoma caninum isolate NT assessed as compound concentration required to inhibit parasitic contraction by larval motility assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 3 Tested
Antiparasitic activity against Ancylostoma caninum isolate PR assessed as compound concentration required to inhibit parasitic contraction by larval arrested morphology assay
Assay data:3 Active, 2 Activity ≤ 1 µM, 4 Tested
Antiparasitic activity against Ancylostoma caninum isolate NT assessed as compound concentration required to inhibit parasitic contraction by larval arrested morphology assay
Ratio of EC50 for Ancylostoma caninum isolate PR to IC50 for Ancylostoma caninum isolate NT by by force transduction assay
Assay data:4 Tested
SummaryPubMed Citation
Antiparasitic activity against Ancylostoma caninum isolate PR assessed as concentration of drug required to cause a force of contraction half that of the KCl-induced maximal contraction by force transduction assay
Antiparasitic activity against Ancylostoma caninum isolate NT assessed as concentration of drug required to cause a force of contraction half that of the KCl-induced maximal contraction by force transduction assay
Antiparasitic activity against Ancylostoma caninum isolate PR assessed as increase in contraction force at 6 to 500 ug/ml by force transduction assay
Assay data:1 Tested
Antiparasitic activity against Ancylostoma caninum isolate NT assessed as increase in contraction force at 6 to 500 ug/ml by force transduction assay
Ratio of IC50 for Ancylostoma caninum isolate NT to IC50 for Ancylostoma caninum isolate PR by larval motility assay
Assay data:3 Tested
Ratio of IC50 for Ancylostoma caninum isolate NT to IC50 for Ancylostoma caninum isolate PR by larval arrested morphology assay
Anthelmintic activity against dog hookworm larvae infected in mouse assessed as protection against infection rate at 0.06%
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