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Parasiticidal activity against Rhipicephalus sanguineus assessed per tick by brown dog tick assay
Assay data:22 Tested
SummaryPubMed Citation
Inhibition of Ixodes ricinus asparaginyl endopeptidases
Assay data:40 Active, 5 Activity ≤ 1 nM, 39 Activity ≤ 1 µM, 54 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of Ixodes ricinus AE expressed in Pichia pastoris after 20 mins
Assay data:25 Active, 3 Activity ≤ 1 nM, 23 Activity ≤ 1 µM, 28 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of Ixodes ricinus CatD expressed in Escherichia coli BL21(DE3) at 50 nM using Abz-Lys-Pro-Ala-Glu-Phe-Nph-Ala-Leu as substrate preincubated for 10 mins followed by substrate addition and measured by FRET assay
Assay data:31 Active, 31 Tested
SummaryCompounds, ActivePubMed Citation
Parasiticidal activity against Rhipicephalus sanguineus assessed as mortality after 24 hrs by brown dog tick assay
Assay data:47 Tested
Parasiticidal activity against Rhipicephalus sanguineus assessed as mortality at 10 ug/tick by brown dog tick assay
Assay data:1 Tested
Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB
Assay data:3916 Active, 206 Activity ≤ 1 nM, 1830 Activity ≤ 1 µM, 3916 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Experimentally measured binding affinity data derived from PDB
Assay data:3073 Active, 3073 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
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