Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Dual-Glo Luciferase Assay from US Patent US11420935: "Bicyclic compounds"
Assay data:150 Active, 140 Activity ≤ 1 µM, 150 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
YAP Reporter Assay from US Patent US11186554: "Non-fused tricyclic compounds"
Assay data:164 Active, 133 Activity ≤ 1 µM, 164 Tested
Enzyme Activity Assay from Article 10.1186/1471-2091-13-3: "Enzymatic activity and immunoreactivity of Aca s 4, an alpha-amylase allergen from the storage mite Acarus siro."
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
NanoLuc Inhibition Assay from Article 10.1021/acschembio.6b01129: "Highly Potent Cell-Permeable and Impermeable NanoLuc Luciferase Inhibitors."
Assay data:41 Active, 29 Activity ≤ 1 µM, 47 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Quantitative Reverse Transcriptase Assay from Article 10.1002/cbic.201402650: "A photorhabdus natural product inhibits insect juvenile hormone epoxide hydrolase."
Assay data:3 Active, 12 Tested
Enzyme Activity Assay from US Patent US8541363: "Pyruvamide compounds as inhibitors of dust mite group 1 peptidase allergen and their use"
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Interaction Assay from Article 10.1021/bi1006354: "Interaction kinetic and structural dynamic analysis of ligand binding to acetylcholine-binding protein."
Assay data:8 Active, 1 Activity ≤ 1 nM, 7 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Radioligand Competition Assay from Article 10.1074/jbc.M111.292243: "Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine α4β2 receptors: unique role of halogen bonding revealed."
Assay data:8 Active, 7 Activity ≤ 1 nM, 8 Activity ≤ 1 µM, 8 Tested
Synthesizing Selective Agonists for the ?7 Nicotinic Receptor with in situ Click-Chemistry on Acetylcholine Binding Protein Templates. from Article 10.1124/mol.112.080291: "Synthesizing Selective Agonists for the ?7 Nicotinic Receptor with in situ Click-Chemistry on Acetylcholine Binding Protein Templates."
Assay data:41 Active, 34 Activity ≤ 1 µM, 43 Tested
Inhibition Assay from Article 10.1002/cbic.200900750: "Structural investigation of the binding of 5-substituted swainsonine analogues to Golgi alpha-mannosidase II."
Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested
Inhibition Assay from Article 10.1002/cbic.200800538: "The molecular basis of inhibition of Golgi alpha-mannosidase II by mannostatin A."
Assay data:4 Active, 4 Activity ≤ 1 µM, 6 Tested
Tryptophan Fluorescence Quenching Assay (Kd) from Article 10.1021/jm900448m: "Flaviviral protease inhibitors identified by fragment-based library docking into a structure generated by molecular dynamics."
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
WNV Protease Inhibition Assay from Article 10.1021/jm900448m: "Flaviviral protease inhibitors identified by fragment-based library docking into a structure generated by molecular dynamics."
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
In Vitro Enzyme Activity Assay from Article 10.1021/bi030031h: "Thermodynamic characterization of the binding of nucleotides to glycyl-tRNA synthetase."
Assay data:2 Active, 2 Activity ≤ 1 µM, 6 Tested
Toxicity against Galleria mellonella larva infected with Candida albicans SC5314 assessed as increase in survival rate at 8 mg/kg measured for 14 days
SummaryPubMed Citation
Neuroprotective activity against transgenic Caenorhabditis elegans CL2355 assessed as A-beta aggregration-induced reversal of disrupted chemotaxis behaviour by measuring chemotaxis index at 1.5 uM treated for 72 hrs followed by compound washout and odorant addition for 1 hr
Assay data:2 Active, 2 Tested
Effect on locomotory activity in transgenic Caenorhabditis elegans CL2006 model of paralysis assessed as reduction in defective locomotion by measuring motor index at 0.1 to 10 uM by motor behaviour assay
Toxicity in Galleria mellonella larvae assessed as change in morphology at 16 ug/ml measured after 5 days by Hematoxylin and eosin staining
Toxicity in Galleria mellonella larvae assessed as melanization of larvae at 16 ug/ml measured every 24 hrs for 4 to 5 days relative to control
Assay data:1 Tested
Toxicity in Galleria mellonella larvae assessed as melanization of larvae at 0.05 ug/ml measured every 24 hrs upto 5 days relative to control
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on