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Fluorescence Polarization Assay from US Patent US11234987: "Isoxazole compounds as inhibitors of heat shock proteins"
Assay data:76 Active, 77 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
Malachite Green ATPase Assay from US Patent US11234987: "Isoxazole compounds as inhibitors of heat shock proteins"
Assay data:57 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Target
Inhibition Assay from Article 10.3109/14756366.2012.727812: "Pyrimidine-fused heterocycle derivatives as a novel class of inhibitors for a-glucosidase."
Assay data:1 Active, 4 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
α-glucosidase Inhibitory Activity Assay from Article 10.3109/14756366.2012.719503: "Structure-activity relationships of bergenin derivatives effect on a-glucosidase inhibition."
Assay data:17 Tested
SummaryPubMed CitationRelated BioAssays by Target
Yeast FTase Assay from Article 10.3109/14756366.2011.643302: "New protein farnesyltransferase inhibitors in the 3-arylthiophene 2-carboxylic acid series: diversification of the aryl moiety by solid-phase synthesis."
Assay data:24 Active, 1 Activity ≤ 1 nM, 14 Activity ≤ 1 µM, 24 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Fluorescence-Based PFTase Inhibition Assay from Article 10.3109/14756360903169592: "Semisynthesis of alpha-methyl-gamma-lactones and in vitro evaluation of their activity on protein farnesyltransferase."
Assay data:2 Active, 2 Activity ≤ 1 µM, 21 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
α-Glucosidase Inhibition Assay from Article 10.1016/j.bioorg.2017.05.009: "Hetarylcoumarins: Synthesis and biological evaluation as potent a-glucosidase inhibitors."
Assay data:5 Active, 11 Tested
SummaryCompounds, ActivePubMed Citation
In Vitro α-Glucosidase Inhibitory Assay from Article 10.1016/j.bioorg.2017.05.006: "Discovery of 3,3-di(indolyl)indolin-2-one as a novel scaffold for a-glucosidase inhibitors: In silico studies and SAR predictions"
Assay data:5 Active, 15 Tested
SummaryCompounds, Active
In Vitro α-Glucosidase Inhibitory Assay from Article 10.1111/cbdd.12867: "Synthesis, in vitro evaluation and molecular docking studies of novel coumarin-isatin derivatives as a-glucosidase inhibitors."
Assay data:10 Active, 21 Tested
Activation Assay from US Patent US9315493: "Phenylpyridine derivative and drug containing same"
Assay data:18 Active, 10 Activity ≤ 1 µM, 18 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
α-Glucosidase Inhibition Assay from Article 10.1016/j.bioorg.2017.03.006: "Synthesis, in vitro evaluation and molecular docking studies of novel amide linked triazolyl glycoconjugates as new inhibitors of a-glucosidase."
Assay data:9 Tested
SummaryPubMed Citation
α-Glucosidase Inhibition Assay from Article 10.1016/j.bioorg.2017.02.003: "Green synthesis, inhibition studies of yeast a-glucosidase and molecular docking of pyrazolylpyridazine amines."
Assay data:11 Tested
α-Glucosidase Inhibition Assay from Article 10.1016/j.bioorg.2017.01.017: "In search of new a-glucosidase inhibitors: Imidazolylpyrazole derivatives."
Assay data:3 Active, 12 Tested
Baker's Yeast α-Glucosidase Inhibition Assay from Article 10.1016/j.bioorg.2016.12.009: "Synthesis, molecular docking studies of hybrid benzimidazole as a-glucosidase inhibitor."
Assay data:18 Tested
Colorimetric Malachite Green Assay from Article 10.1021/acschembio.6b00510: "Discovery of Allosteric and Selective Inhibitors of Inorganic Pyrophosphatase from Mycobacterium tuberculosis."
Assay data:14 Tested
α-Glucosidase inhibition assay from Article 10.1016/j.bioorg.2016.08.011: "A simple and efficient synthesis of novel inhibitors of alpha-glucosidase based on benzimidazole skeleton and molecular docking studies."
Assay data:8 Tested
Radioactive Assay from Article 10.1021/acs.biochem.6b00486: "Fluorescent Farnesyl Diphosphate Analogue: A Probe To Validate trans-Prenyltransferase Inhibitors."
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Fluorescent Assay from Article 10.1021/acs.biochem.6b00486: "Fluorescent Farnesyl Diphosphate Analogue: A Probe To Validate trans-Prenyltransferase Inhibitors."
In vitro Assay of alpha-Glucosidasee Inhibitory Activity from Article 10.1016/j.bioorg.2016.03.001: "Design, synthesis and biological evaluation of novel coumarin thiazole derivatives as a-glucosidase inhibitors."
Assay data:2 Active, 18 Tested
Assay for α-Glucosidase Inhibitory Activity from Article 10.1016/j.bioorg.2016.02.004: "Synthesis, a-glucosidase inhibitory, cytotoxicity and docking studies of 2-aryl-7-methylbenzimidazoles."
Assay data:2 Active, 1 Activity ≤ 1 µM, 20 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
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