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Nematicidal activity against Caenorhabditis elegans incubated for 18 hrs
Assay data:8 Tested
SummaryPubMed Citation
Inhibition of CDC7 in transgenic Caenorhabditis elegans CK423 Bus-8(e2698) expressing human TDP-43 assessed as inhibition of TDP-43 phosphorylation at 10 to 75 uM measured after 6 days by Western blot assay
Assay data:2 Tested
Inhibition of CDC7 in transgenic Caenorhabditis elegans CK423 Bus-8(e2698) expressing human TDP-43 assessed as inhibition of TDP-43 phosphorylation at 75 uM measured after 6 days by Western blot assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Induction of autophagy in Caenorhabditis elegans BC12921 expressing SQST-1-GFP fusion protein assessed as decrease in fluorescence intensity at 1 uM by microplate reader analysis
Growth inhibition of Caenorhabditis elegans N2 assessed as reduction in body size at 10 mM in presence of D-fructose by microscopic method
Assay data:1 Tested
Growth inhibition of Caenorhabditis elegans N2 assessed as reduction in body size at 10 mM in presence of 125 mM D-glucose by microscopic method
Growth inhibition of Caenorhabditis elegans N2 assessed as reduction in body size at 10 mM in presence of D-ribose by microscopic method
Growth inhibition of Caenorhabditis elegans N2 L1 larvae under monoxenic condition assessed as reduction in body size at 42 mM incubated for 72 hrs by microscopic method relative to control
Toxicity in Caenorhabditis elegans N2 under monoxenic condition with Escherichia coli food assessed as mortality at 42 mM incubated for 72 hrs by microscopic method relative to control
Growth inhibition of Caenorhabditis elegans N2 L1 larvae under monoxenic condition with Escherichia coli food assessed as reduction in motility at 42 mM incubated for 72 hrs by microscopic method relative to control
Growth inhibition of Caenorhabditis elegans N2 L1 larvae under monoxenic condition with Escherichia coli food assessed as reduction in body size at 42 mM incubated for 72 hrs by microscopic method relative to control
Assay data:9 Tested
Growth inhibition of Caenorhabditis elegans N2 L1 larvae under axenic condition assessed as reduction in body size at 16 mM incubated for 7 days by microscopic method relative to control
Activation of CREB in radioactive-induced Caenorhabditis elegans MY36 harboring [crh-1(tz2); Pmbr-1-mcherry::crh-1(mtIs18)] mutant assessed as increase in long-term memory preincubated for 24 hrs followed by gamma-radiation treatment and measured after 24 hrs
Activation of CREB in radioactive-induced Caenorhabditis elegans YT17 harboring crh-1(tz2) mutant assessed as reduction radiation-induced damage preincubated for 24 hrs followed by gamma-radiation treatment and measured after 24 hrs
Activation of CREB in radioactive-induced Caenorhabditis elegans YT17 harboring crh-1(tz2) mutant assessed as increase in long-term memory preincubated for 24 hrs followed by gamma-radiation treatment and measured after 24 hrs
Memory enhancement effect in radioactive-induced Caenorhabditis elegans assessed as increase in cAMP level preincubated for 24 hrs followed by gamma-radiation treatment and measured after 24 hrs
Memory enhancement effect in radioactive-induced Caenorhabditis elegans harboring RNAi podr-1::unc-31 mutant assessed as memory index preincubated for 24 hrs followed by gamma-radiation treatment and measured after 24 hrs
Memory enhancement effect in radioactive-induced Caenorhabditis elegans RB1341 harboring npl-1(ok1470) mutant assessed as memory index preincubated for 24 hrs followed by gamma-radiation treatment and measured after 24 hrs
Memory enhancement effect in radioactive-induced Caenorhabditis elegans harboring RNAi egl8;egl-30(n686)ls(Podr-1-mcherry::egl-30) mutant assessed as memory index preincubated for 24 hrs followed by gamma-radiation treatment and measured after 24 hrs
Memory enhancement effect in radioactive-induced Caenorhabditis elegans MY66 harboring egl-30(n686);Podr-1-mcherry::egl-30(mtIs35)] mutant assessed as memory index preincubated for 24 hrs followed by gamma-radiation treatment and measured after 24 hrs
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