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Antagonist activity at cADPR binding protein in sea urchin egg homogenate assessed as inhibition of cADPR-induced Ca2+ release by Fluo-3 based fluorescence assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antagonist activity at cADPR binding protein in sea urchin egg homogenate assessed as decrease in cADPR-induced Ca2+ release at 23 uM by Fluo-3 based fluorescence assay
Assay data:1 Tested
SummaryPubMed Citation
Agonist activity at cADPR binding protein in sea urchin egg homogenate assessed as increase in Ca2+ release at 100 uM by Fluo-3 based fluorescence assay relative to control
Agonist activity at cADPR binding protein in sea urchin egg homogenate assessed as increase in Ca2+ release at lowest concentration by Fluo-3 based fluorescence assay
Agonist activity at cADPR binding protein in sea urchin egg homogenate assessed as increase in Ca2+ release by Fluo-3 based fluorescence assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of first cleavage in sea urchin embryo after 1.5 hrs by microscopy
Assay data:17 Tested
Summary
Inhibition of fertilized sea urchin egg cell division
Assay data:2 Tested
Inhibition of sea urchin egg fertilization after 10 mins
Assay data:10 Tested
Antimitotic activity against sea urchin embryo assessed as cleavage arrest measured 2.5 to 5.5 hrs post-fertilization using compound stored for 4.5 days in 96% EtOH at room temperature by light microscopy analysis
Antimitotic activity against sea urchin embryo assessed as cleavage arrest measured 2.5 to 5.5 hrs post-fertilization using compound stored for 2.5 days in 96% EtOH at room temperature by light microscopy analysis
Antimitotic activity against sea urchin embryo assessed as cleavage arrest measured 2.5 to 5.5 hrs post-fertilization using compound stored for 13 hrs in 96% EtOH at room temperature by light microscopy analysis
Antimitotic activity against sea urchin embryo assessed as cleavage arrest measured 2.5 to 5.5 hrs post-fertilization using compound stored for 1 month in 96% EtOH at room temperature by light microscopy analysis
Antimitotic activity against sea urchin embryo assessed as cleavage arrest measured 2.5 to 5.5 hrs post-fertilization using compound stored for 4 days in 96% EtOH at room temperature by light microscopy analysis
Antimitotic activity against sea urchin embryo assessed as cleavage arrest measured 2.5 to 5.5 hrs post-fertilization using compound stored for 2 days in 96% EtOH at room temperature by light microscopy analysis
Antimitotic activity against sea urchin embryo assessed as cleavage arrest measured 2.5 to 5.5 hrs post-fertilization using compound stored for 1 hr in 96% EtOH at room temperature by light microscopy analysis
Assay data:4 Active, 4 Activity ≤ 1 µM, 5 Tested
Antimitotic activity against sea urchin embryo assessed as cleavage alteration measured 2.5 to 5.5 hrs post-fertilization using compound stored for 4.5 days in 96% EtOH at room temperature by light microscopy analysis
Antimitotic activity against sea urchin embryo assessed as cleavage alteration measured 2.5 to 5.5 hrs post-fertilization using compound stored for 2.5 days in 96% EtOH at room temperature by light microscopy analysis
Antimitotic activity against sea urchin embryo assessed as cleavage alteration measured 2.5 to 5.5 hrs post-fertilization using compound stored for 13 hrs in 96% EtOH at room temperature by light microscopy analysis
Antimitotic activity against sea urchin embryo assessed as cleavage alteration measured 2.5 to 5.5 hrs post-fertilization using compound stored for 1 month in 96% EtOH at room temperature by light microscopy analysis
Antimitotic activity against sea urchin embryo assessed as cleavage alteration measured 2.5 to 5.5 hrs post-fertilization using compound stored for 4 days in 96% EtOH at room temperature by light microscopy analysis
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