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Antibacterial activity against metronidazole-resistant Bacteroides thetaiotaomicron MMX 3409
Assay data:4 Tested
SummaryPubMed Citation
Inhibition of Bacteroides thetaiotaomicron BexA expressed in Escherichia coli KAM32 assessed as inhibition of bacterial growth incubated for 18 hrs by microbroth dilution method
Assay data:3 Tested
The compound (1 mg/mL, 80 microL/6.5 mm) was tested for zone of inhibition against Bacteroides thetaiotaomicron UC 6360
Assay data:1 Tested
Summary
Inhibition of Bacteroides thetaiotaomicron beta-N-acetylglucosaminidase GH84 using p-nitrophenyl 2-acetamido-2-deoxy-beta-D-glucosaminide substrate at pH 7.0 and 25 degC
Assay data:1 Active, 1 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of Bacteroides thetaiotaomicron recombinant alpha-L-fucosidase using 2-chloro-4-nitrophenyl-alpha-L-fucopyranoside as substrate after 5 mins by Michaelis Menten equation analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3994 assessed as reduction of mannose release using 4NP-mannopyranoside substrate
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3991 assessed as reduction of mannose release using 4NP-mannopyranoside substrate
Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3990 assessed as reduction of mannose release using 4NP-mannopyranoside substrate
Assay data:1 Active, 4 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3965 assessed as reduction of mannose release using 4NP-mannopyranoside substrate
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3130 assessed as reduction of mannose release using 4NP-mannopyranoside substrate
Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 2199 assessed as reduction of mannose release using 4NP-mannopyranoside substrate
Binding affinity to Bacteroides thetaiotaomicron N-acetyl-glucosaminidase
Inhibition of Bacteroides thetaiotaomicron beta-mannosidase 2A N461A mutant expressed in Escherichia coli assessed as inhibition of 4-methyllumbelliferone release by spectrophotometry
Assay data:2 Active, 8 Tested
Inhibition of Bacteroides thetaiotaomicron beta-mannosidase 2A W395A mutant expressed in Escherichia coli assessed as inhibition of 4-methyllumbelliferone release by spectrophotometry
Assay data:8 Tested
Inhibition of Bacteroides thetaiotaomicron beta-mannosidase 2A W645A mutant expressed in Escherichia coli assessed as inhibition of 4-methyllumbelliferone release by spectrophotometry
Assay data:1 Active, 8 Tested
Inhibition of Bacteroides thetaiotaomicron beta-mannosidase 2A W198G mutant expressed in Escherichia coli assessed as inhibition of 4-methyllumbelliferone release by spectrophotometry
Inhibition of Bacteroides thetaiotaomicron beta-mannosidase 2A Y537A mutant expressed in Escherichia coli assessed as inhibition of 4-methyllumbelliferone release by spectrophotometry
Assay data:5 Active, 1 Activity ≤ 1 µM, 8 Tested
Inhibition of Bacteroides thetaiotaomicron beta-mannosidase 2A Q646A mutant expressed in Escherichia coli assessed as inhibition of 4-methyllumbelliferone release by spectrophotometry
Assay data:5 Active, 3 Activity ≤ 1 µM, 8 Tested
Inhibition of wild type Bacteroides thetaiotaomicron beta-mannosidase 2A expressed in Escherichia coli assessed as inhibition of 4-methyllumbelliferone release by spectrophotometry
Assay data:6 Active, 3 Activity ≤ 1 µM, 8 Tested
Inhibition of wild type Bacteroides thetaiotaomicron beta-mannosidase 2A expressed in Escherichia coli BL21 (DE3) at 37 degC and Ph 5.6 by 2,4-dinitrophenolate release assay
Assay data:11 Active, 5 Activity ≤ 1 µM, 25 Tested
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