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Dual-Glo Luciferase Assay from US Patent US11420935: "Bicyclic compounds"
Assay data:150 Active, 140 Activity ≤ 1 µM, 150 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
YAP Reporter Assay from US Patent US11186554: "Non-fused tricyclic compounds"
Assay data:164 Active, 133 Activity ≤ 1 µM, 164 Tested
Enzyme Activity Assay from Article 10.1186/1471-2091-13-3: "Enzymatic activity and immunoreactivity of Aca s 4, an alpha-amylase allergen from the storage mite Acarus siro."
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
NanoLuc Inhibition Assay from Article 10.1021/acschembio.6b01129: "Highly Potent Cell-Permeable and Impermeable NanoLuc Luciferase Inhibitors."
Assay data:41 Active, 29 Activity ≤ 1 µM, 47 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Quantitative Reverse Transcriptase Assay from Article 10.1002/cbic.201402650: "A photorhabdus natural product inhibits insect juvenile hormone epoxide hydrolase."
Assay data:3 Active, 12 Tested
Enzyme Activity Assay from US Patent US8541363: "Pyruvamide compounds as inhibitors of dust mite group 1 peptidase allergen and their use"
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition Assay from Article 10.1002/cbic.200900750: "Structural investigation of the binding of 5-substituted swainsonine analogues to Golgi alpha-mannosidase II."
Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested
Inhibition Assay from Article 10.1002/cbic.200800538: "The molecular basis of inhibition of Golgi alpha-mannosidase II by mannostatin A."
Assay data:4 Active, 4 Activity ≤ 1 µM, 6 Tested
Tryptophan Fluorescence Quenching Assay (Kd) from Article 10.1021/jm900448m: "Flaviviral protease inhibitors identified by fragment-based library docking into a structure generated by molecular dynamics."
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
WNV Protease Inhibition Assay from Article 10.1021/jm900448m: "Flaviviral protease inhibitors identified by fragment-based library docking into a structure generated by molecular dynamics."
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
In Vitro Enzyme Activity Assay from Article 10.1021/bi030031h: "Thermodynamic characterization of the binding of nucleotides to glycyl-tRNA synthetase."
Assay data:2 Active, 2 Activity ≤ 1 µM, 6 Tested
Toxicity against Galleria mellonella larva infected with Candida albicans SC5314 assessed as increase in survival rate at 8 mg/kg measured for 14 days
SummaryPubMed Citation
Toxicity in Galleria mellonella larvae assessed as change in morphology at 16 ug/ml measured after 5 days by Hematoxylin and eosin staining
Toxicity in Galleria mellonella larvae assessed as melanization of larvae at 16 ug/ml measured every 24 hrs for 4 to 5 days relative to control
Assay data:1 Tested
Toxicity in Galleria mellonella larvae assessed as melanization of larvae at 0.05 ug/ml measured every 24 hrs upto 5 days relative to control
Toxicity in Galleria mellonella larvae assessed as melanization of larvae at 0.23 ug/ml measured every 24 hrs upto 5 days relative to control
Toxicity in Galleria mellonella larvae assessed as melanization of larvae at 16 ug/ml measured every 24 hrs upto 5 days relative to control
Toxicity against Galleria mellonella assessed as survival at 5 to 128 mg/kg measured after 5 days
Larvicidal activity against Plutella xylostella assessed as mortality and measured upto 4 days
Insecticidal activity against third instar larvae of Helicoverpa armigera (cotton bollworms) measured after 24 hrs
Assay data:6 Tested
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