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Surface Plasmon Resonance (SPR) assay from OICR from Article : "Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor."
Assay data:38 Active, 3 Activity ≤ 1 nM, 38 Activity ≤ 1 µM, 50 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Surface Plasmon Resonance (SPR) assay from Article : "Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor."
Assay data:38 Active, 3 Activity ≤ 1 nM, 37 Activity ≤ 1 µM, 52 Tested
Fluorescence Polarization (FP) Assays from Article : "Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor."
Assay data:7 Active, 3 Activity ≤ 1 µM, 25 Tested
MIF Enzymatic Assay from US Patent US11884682: "Compounds and their uses as MIF inhibitors"
Assay data:53 Active, 35 Activity ≤ 1 µM, 86 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Enzyme Assay from US Patent US11884671: "Purinone compounds and their use in treating cancer"
Assay data:51 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Target
Assay data:1 Active, 51 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
TTK Enzyme Assay from US Patent US11884671: "Purinone compounds and their use in treating cancer"
Assay data:46 Active, 22 Activity ≤ 1 µM, 51 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
DNAPK Enzyme Potency Assay (DNA-PK Enz) from US Patent US11884671: "Purinone compounds and their use in treating cancer"
Assay data:51 Active, 43 Activity ≤ 1 nM, 51 Activity ≤ 1 µM, 51 Tested
Biochemical Assay from US Patent US11884660: "Substituted oxopyridine derivative"
Assay data:2 Tested
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
HPK1 Kinase Assay (Biochemical Assay) from US Patent US20240025922: "TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS"
Assay data:181 Active, 187 Activity ≤ 1 µM, 187 Tested
KRAS G12D LoEnz Biochemical Assay from US Patent US20240025919: "AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF"
Assay data:255 Active, 170 Activity ≤ 1 nM, 252 Activity ≤ 1 µM, 258 Tested
KRAS WT Biochemical Assay from US Patent US20240025919: "AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF"
Assay data:50 Active, 8 Activity ≤ 1 nM, 45 Activity ≤ 1 µM, 56 Tested
RIPK1-ADP-Glo Enzymatic Assay from US Patent US20240025912: "RIPK1 INHIBITORS AND METHODS OF USE"
Assay data:108 Active, 108 Activity ≤ 1 µM, 108 Tested
Inhibitory Activity of the Compounds of the Invention Against ROS1, NTRK and ALK and their Drug-Resistant Kinases from US Patent US20240025908: "COMPOUND USED AS KINASE INHIBITOR AND USE THEREOF"
Assay data:29 Active, 14 Activity ≤ 1 nM, 29 Activity ≤ 1 µM, 29 Tested
In Vitro DGKα and DGKζ Inhibition Assay from US Patent US20240025900: "TETRACYCLIC COMPOUNDS AS DGK INHIBITORS"
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
ATR Enzyme Assay from US Patent US20240025899: "TRIHETEROCYCLIC DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF"
Assay data:11 Active, 2 Activity ≤ 1 nM, 11 Activity ≤ 1 µM, 11 Tested
Measurement of Human IRAK-4 Inhibitory Activity from US Patent US20240025893: "PYRIMIDINE-AND NITROGEN-CONTAINING BICYCLIC COMPOUND"
Assay data:248 Active, 20 Activity ≤ 1 nM, 248 Activity ≤ 1 µM, 248 Tested
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