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Fluorescent dye transport assay for SLC1A3 using HEK293 JumpIn SLC1A3 OE cells
Assay data:3 Active, 3 Tested
SummaryRelated BioAssays by Target
Fluorescent dye transport assay for SLC7A3 using HEK293 JumpIn SLC7A3 OE cells
Impedance-based phenotypic for SLC1A3 using HEK JumpIn SLC1A3 OE cells
Assay data:6 Active, 6 Tested
Impedance-based transport assay for SLC22A3 using HEK293 JumpIn SLC22A3 OE cells
Assay data:5 Active, 5 Tested
Impedance-based TRACT assay for SLC6A2 using HEK293 JumpIn SLC6A2 OE cells
Assay data:15 Active, 15 Tested
Impedance-based transporter assay for SLC29A1 using U2OS cells
Impedance-based TRACT assay for SLC6A3 using HEK293 JumpIn SLC6A3 OE cells
qHTS for Inhibitors of ATXN expression: Summary
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS for Inhibitors of ATXN expression: Validation
Assay data:73 Active, 17 Activity ≤ 1 µM, 1280 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS for Inhibitors of ATXN expression: Validation of Cytotoxic Assay
Assay data:44 Active, 10 Activity ≤ 1 µM, 1280 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
Assay data:1940 Active, 33 Activity ≤ 1 nM, 9672 Activity ≤ 1 µM, 397420 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Selectivity index, ratio of GI50 for human L-132 cells to GI50 for human HepG2 cells
Assay data:2 Tested
SummaryPubMed Citation
Selectivity index, ratio of GI50 for human L-132 cells to GI50 for human MCF7 cells
Growth inhibition of human L-132 cells by MTT assay
SummaryCompounds, ActivePubMed Citation
Growth inhibition of human MCF7 cells by MTT assay
Assay data:20 Active, 22 Tested
Growth inhibition of human HepG2 cells by MTT assay
Assay data:16 Active, 22 Tested
Growth inhibition of human MCF7 cells at 10 uM by MTT assay relative to control
Assay data:39 Tested
Growth inhibition of human HepG2 cells at 10 uM by MTT assay relative to control
Antiproliferative activity against human PC3 cells at 20 ug/ml after 24 hrs by MTT assay
Agonist activity at human BRS3 expressed in CHOK1 cells measured after 1 hrs by IP-One HTRF assay
Assay data:18 Active, 2 Activity ≤ 1 nM, 16 Activity ≤ 1 µM, 20 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
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