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Enzyme Inhibition Assay from Article 10.3109/14756366.2010.548329: "Synthesis and biological evaluation of novel N,N'-bis-methylenedioxybenzyl-alkylenediamines as bivalent anti-Alzheimer disease ligands."
Assay data:6 Active, 8 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of equine serum BuChE using S-butyrylthiocholine as substrate at by DTNB reagent based spectrophotometric analysis
Assay data:1 Active, 1 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of equine serum BuChE using S-butyrylthiocholine as substrate at 100 uM by DTNB reagent based spectrophotometric analysis
Assay data:6 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of equine serum BChE using butyrylthiocholine as substrate preincubated for 60 mins by Ellman's method
Assay data:1 Active, 1 Tested
Inhibition of equine BChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's method
Assay data:3 Tested
Inhibition of horse BChE using butyrylthiocholine as substrate measured for 5 mins by Ellman's method
Inhibition of equine serum BChE using S-butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by Ellman's method
Assay data:2 Active, 2 Tested
Inhibition of equine BChE
Assay data:12 Active, 8 Activity ≤ 1 µM, 13 Tested
Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and measured after 20 mins by Ellman's method
Assay data:1 Active, 34 Tested
Inhibition of equine serum BChE at 50 uM using butyrylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and measured after 20 mins by Ellman's method
Assay data:33 Tested
Inhibition of equine serum BuChE using butylthiocholine as substrate preincubated for 15 mins followed by substrate addition and measured after 8 mins by spectrophotometric analysis
Assay data:11 Tested
Potency index,ratio of isatin IC50 to test compound IC50 for inhibition of equine serum BuChE
Assay data:1 Tested
Mixed reversible inhibition of equine serum BuChE assessed as decrease in Vmax and increase in Km at 1.56 to 6.25 uM by Lineweaver-burk plot analysis
Mixed reversible inhibition of equine serum BuChE assessed as decrease in Vmax and increase in Km at 3.13 to 12.5 uM by Lineweaver-burk plot analysis
Inhibition of equine serum BuChE by Ellman's method
Assay data:6 Active, 1 Activity ≤ 1 µM, 18 Tested
Mixed type inhibition of equine liver glutathione S-transferase using CDNB as substrate assessed as inhibition constant of ESI complex by Lineweaver-burk plot analysis
SummaryPubMed Citation
Mixed type inhibition of equine liver glutathione S-transferase using CDNB as substrate assessed as inhibition constant of ES complex by Lineweaver-burk plot analysis
Mixed type inhibition of equine liver glutathione S-transferase using GSH as substrate assessed as inhibition constant of ESI complex by Lineweaver-burk plot analysis
Mixed type inhibition of equine liver glutathione S-transferase using GSH as substrate assessed as inhibition constant of ES complex by Lineweaver-burk plot analysis
Inhibition of equine liver glutathione S-transferase at 2.5 uM in the presence of DTT and UV irradiation
SummaryCompounds, ActivePubMed Citation
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