BioAssay by Target (List) for Gene (Select 10746) - PubChem BioAssay - NCBI

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Select item 19136211.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000178b MAP3K2

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:1 Tested

AID:: 1913621

Summary Related BioAssays by Target

Select item 19136202.

Selectivity interaction (KinomeScan (DiscoverX, competition-binding assay)) EUB0000178b MAP3K2

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913620

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19136193.

Selectivity interaction (Enzymatic assay) EUB0000178b MAP3K2

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913619

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 18619854.

Inhibition of MEKK2 (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:2 Tested

AID:: 1861985

Summary PubMed Citation Related BioAssays by Target

Select item 18565625.

Inhibition of wild-type human partial length MAP3K2 (S315 to H619 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:1 Tested

AID:: 1856562

Summary PubMed Citation Related BioAssays by Target

Select item 18356316.

MAP3K2 DiscoveRx kinase panel

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:1 Tested

AID:: 1835631

Summary Related BioAssays by Target

Select item 18350397.

MEKK2(h) Kinase panel

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:1 Tested

AID:: 1835039

Summary Related BioAssays by Target

Select item 18342108.

Inhibition of MEKK2 (unknown origin) at 1 uM

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:1 Tested

AID:: 1834210

Summary PubMed Citation Related BioAssays by Target

Select item 17941729.

KinomeScan assay: inhibition of MAP3K2

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:1 Active, 108 Tested

AID:: 1794172

Summary Compounds, Active Related BioAssays by Target

Select item 179388810.

MEKK2 [MAP3K2(M3K2LGF1)] Takeda global kinase panel

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793888

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179274611.

MEKK2(h) Eurofins kinase panel

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:1 Tested

AID:: 1792746

Summary Related BioAssays by Target

Select item 179236012.

MEKK2 ProQinase selectivity panel

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:1 Tested

AID:: 1792360

Summary Related BioAssays by Target

Select item 179106313.

MAP3K2 (MEKK2) Kinase screen

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:1 Tested

AID:: 1791063

Summary Related BioAssays by Target

Select item 179024314.

MAP3K2 Invitrogen selectivity data (BI)

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:1 Tested

AID:: 1790243

Summary Related BioAssays by Target

Select item 178934515.

MEKK2(h) Eurofins Kinase panel

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:1 Tested

AID:: 1789345

Summary Related BioAssays by Target

Select item 178739216.

MEKK2(h) Millipore kinase panel

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:1 Tested

AID:: 1787392

Summary Related BioAssays by Target

Select item 178644317.

MAP3K2 Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:1 Tested

AID:: 1786443

Summary Related BioAssays by Target

Select item 178600418.

MEKK2 Kinase panel

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:1 Tested

AID:: 1786004

Summary Related BioAssays by Target

Select item 177192019.

Binding affinity to human MAP3K2 by KINOMEscan scanMAX assay

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1771920

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 177191220.

Binding affinity to human MAP3K2 at 1 uM by KINOMEscan scanMAX assay relative to control

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 2

Assay data:1 Tested

AID:: 1771912

Summary PubMed Citation Related BioAssays by Target

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Target

Proteins (2)
BioAssays with protein sequences specified as targets
RNAi Target, Active (8)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (20)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (15)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (22)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (40)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (112)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (44)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (2)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (88)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (65)
BioAssays deposited by other experimentalists

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