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Antagonist activity at muscarinic receptor in BALB/c mouse MSC assessed as inhibition of carbachol-induced increase in cell viability at 10'-10M incubated for 24 hrs by Cell-titer 96 aqueous one solution reagent based assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Antagonist activity at muscarinic receptor in BALB/c mouse MSC assessed as inhibition of carbachol-induced increase in cell viability at 10'-4 to 10'-10M incubated for 24 hrs by Cell-titer 96 aqueous one solution reagent based assay
Activity at muscarinic receptor in BALB/c mouse MSC assessed as increase in cell viability at 10'-10M incubated for 24 hrs by Cell-titer 96 aqueous one solution reagent based assay
Assay data:2 Active, 2 Tested
Activity at muscarinic receptor in BALB/c mouse MSC assessed as reduction in cell viability at 10'-4M incubated for 24 hrs by Cell-titer 96 aqueous one solution reagent based assay
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Antagonist activity at muscarinic M3 receptor in CD1 mouse detrusor muscle assessed as reduction of EFS-elicited contraction at 1 uM
Percent inhibition of radioligand [3H]QNB binding to muscarinic receptor at 10 uM concentration
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Maximum stimulation at Muscarinic acetylcholine receptor M3 expressed in A9 L cells
Assay data:13 Tested
Binding affinity (low) of [3H](R)-QNB binding to Muscarinic acetylcholine receptor M3 expressed in A9 L cell line
Assay data:5 Active, 3 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity (high) of [3H](R)-QNB binding to Muscarinic acetylcholine receptor M3 expressed in A9 L cell line
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Percent inhibition (low) of [3H](R)-QNB binding to Muscarinic acetylcholine receptor M3 expressed in A9 L cell line
Assay data:4 Tested
Percent inhibition (high) of [3H](R)-QNB binding to Muscarinic acetylcholine receptor M3 expressed in A9 L cell line
Assay data:3 Tested
Tested against Muscarinic acetylcholine receptor M3 expressed in A9 L cell line
Assay data:6 Active, 14 Tested
Dissociation constant towards Muscarinic acetylcholine receptor was determined by using [3H]4NMPB as radioligand
Compound was tested for the binding affinity towards muscarinic acetylcholine receptor in mouse brain membrane
Compound was tested for the binding affinity towards muscarinic receptor in mouse brain membrane
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