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CSNK2A1A SGC Tm panel (DSF)
Assay data:1 Tested
SummaryRelated BioAssays by Target
CSNK2A1 SGC Tm panel (DSF)
Binding affinity to C-terminal Nano-Luc fused human CK2alpha expressed in digitonin -permeabilized human HEK293 cells using NanoBRET NanoGlo substrate in presence of tracer K10 by NanoBRET assay
Assay data:27 Active, 27 Tested
Inhibition of wild type human CK2alpha in presence of ATP by radiometric kinase assay
Assay data:1 Active, 2 Tested
Inhibition of wild type human CK2alpha at 1 uM by DiscoverX scanMAX assay relative to control
Assay data:2 Tested
Inhibition of C-terminal Nano-Luc fused human CK2alpha expressed in HEK293 cells using NanoBRET NanoGlo substrate in presence of tracer K10 by NanoBRET assay
Assay data:26 Active, 22 Activity ≤ 1 µM, 27 Tested
Inhibition of CK2A1 (unknown origin)
Binding affinity to CK2alpha (unknown origin) assessed as dissociation constant
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of recombinant human CK2 using RRRDDDSDDD as substrate in presence of [gamma-33P-ATP] incubated for 20 mins by beta-counter analysis
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of CK2 (unknown origin)
Assay data:1 Active, 1 Tested
Inhibition of human CK2alpha using RRRADDSDDDDD as substrate incubated for 30 mins by [gamma-32P]-ATP based scintillation counting analysis
Assay data:1 Active, 3 Tested
Assay data:1 Active, 1 Activity ≤ 1 µM, 4 Tested
Biochemical Assay for Inhibitors of CK2α Kinase Activity Assay from US Patent US11866436: "Benzo[c][2,6]naphthyridine derivatives, compositions and therapeutic uses thereof"
Assay data:181 Active, 118 Activity ≤ 1 nM, 181 Activity ≤ 1 µM, 181 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Radiometric Kinase Assay from US Patent US20230278983: "INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER"
Assay data:85 Active, 71 Activity ≤ 1 µM, 90 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
CK2 Assay (20 uM ATP) from US Patent US8168651: "Protein kinase modulators"
Assay data:52 Active, 44 Activity ≤ 1 µM, 53 Tested
CK2 Assay (15 uM ATP) from US Patent US8168651: "Protein kinase modulators"
Assay data:179 Active, 197 Activity ≤ 1 µM, 200 Tested
CK2 Assay from US Patent US8168651: "Protein kinase modulators"
Assay data:35 Active, 23 Activity ≤ 1 µM, 64 Tested
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