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Selectivity interaction (Serine protease panel) EUB0000735a CTSG
Assay data:1 Tested
SummaryRelated BioAssays by Target
Selectivity interaction (Protease panel (enzymatic assay)) EUB0000239b CTSG
Inhibition of human neutrophil cathepsin G at 100 uM using Suc-Ala-Ala-Pro-Phe-AMC as substrate preincubated for 15 mins followed by addition of substrate measured after 30 mins by measuring amount of AMC formed spectrofluorimetric method
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human neutrophil cathepsin G using Suc-Ala-Ala-Pro-Phe-AMC as substrate preincubated for 15 mins followed by addition of substrate measured after 30 mins by measuring amount of AMC formed spectrofluorimetric method
Inhibition of human Cathepsin G preincubated for 5 mins followed by substrate addition by fluorometer analysis
Binding affinity to human neutrophil cathepsin G assessed as inhibition constant using Succinyl-L-alanyl-L-alanyl-L-prolyl-Lphenylalanine p-Nitroaniline as substrate measured upto 120 mins by spectrophotometric analysis
Cathepsin G Assay from US Patent US9695194: "Benzoxazinone derivatives for treatment of skin diseases"
Assay data:15 Active, 9 Activity ≤ 1 µM, 18 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Peptidase, CTSG (Cathepsin G) Eurofins-Panlabs enzyme assay
Cathepsin G (h) Protease assay
Cathepsin G (h) Eurofins-Cerep enzyme and uptake assay
PEPCATHEPSG Eurofins-Panlabs selectivity data (BI)
CATHEPSG(H) Eurofins SafetyScreen44 (BI)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
PEPCATHEPSG Eurofins SafetyScreen44 (BI)
Inhibition of cathepsin G (unknown origin) at 10 uM
Assay data:3 Tested
Inhibition of human cathepsin G at 100 uM preincubated for 30 mins followed by FP-rhodamine addition measured after 30 mins by fluorescence assay
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of cathepsin G (unknown origin) at 10 uM relative to control
Inhibition of mammalian cathepsin G (unknown origin) using Suc-AAPF-AMC as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins
Inhibition of endogenous human cathepsin G at 10 uM using Suc-Ala-Ala-Pro-Phe-AMC as substrate after 30 mins by spectrophotometric analysis relative to control
Inhibition of cathepsin G (unknown origin) using Suc-AAPF-pNA as substrate preincubated for 20 mins followed by substrate addition by fluorescence plate reader analysis
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