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Inhibition of mouse HCN2 expressed in HEK293 cells assessed as reduction in hyperpolarization activated current at holding potential of -80 mV by patch clamp assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Activation of recombinant mouse HCN2 expressed in Xenopus laevis oocyte assessed as increase in current amplitude at -30 mV holding potential by patch-clamp electrophysiology method
Assay data:5 Active, 1 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Mouse HCN2 (Cyclic nucleotide-regulated channels)
Assay data:7 Active, 7 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Blockade of mouse HCN2 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assay
Assay data:3 Active, 9 Tested
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