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GPCR beta-arrestin recruitment assay with target: CX3CR1 Assay Type: PRESTO-Tango Concentration: 0.0000004
Assay data:211 Tested
SummaryRelated BioAssays by Target
GPCR beta-arrestin recruitment assay with target: CX3CR1 Assay Type: PRESTO-Tango Concentration: 0.000002
GPCR beta-arrestin recruitment assay with target: CX3CR1 Assay Type: PRESTO-Tango Concentration: 0.00001
Assay data:437 Tested
Antagonist activity against CX3CR1 (unknown origin) assessed as inhibition of beta-arrestin 2 recruitment at 10 microM by beta arrestin assay relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity against CX3CR1 (unknown origin) assessed as induction of beta-arrestin 2 recruitment at 10 microM by beta arrestin assay relative to control
PRESTO-Tango GPCRome screening (CX3CR1)
Agonist activity at human CX3CR1 expressed in CHO-K1 cells at 20 uM by PathHunter beta-arrestin assay relative to control
Assay data:8 Tested
Antagonist activity at human CX3CR1 expressed in CHO-K1 cells by PathHunter beta-arrestin assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Antagonist activity at human CX3CR1 expressed in CHO-K1 cells at 20 uM by PathHunter beta-arrestin assay relative to control
Antagonist activity at human Gi/G0-coupled CX3CR1 expressed in CHOK1 cells assessed as inhibition of CX3CL1-induced beta arrestin2 recruitment at 500 nM preincubated for 30 mins followed by CX3CL1 stimulation and measured after 90 to 180 mins by pathhunter assay
Antagonist activity at CX3CR1 (unknown origin) expressed in mouse B300 cells assessed as inhibition of fractalkine-induced chemotaxis incubated for 30 mins and measured after 3.5 hrs by Cell Titer assay
Assay data:12 Active, 12 Activity ≤ 1 µM, 12 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Activity at human CX3CR1 receptor at 10 uM
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Antagonist activity at CX3CR1 (unknown origin)
Agonist activity at CX3CR1 (unknown origin)
Human CX3CR1 (Chemokine receptors)
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
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