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Potency index, ratio of neamine IC50 to test compound IC50 for [3H]Rev response element binding to HIV1 biotinylated-Rev protein expressed in Escherichia coli
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Potency index, ratio of neomycin IC50 to test compound IC50 for [3H]Rev response element binding to HIV1 biotinylated-Rev protein expressed in Escherichia coli
Inhibition of [3H]Rev response element binding to HIV1 biotinylated-Rev protein expressed in Escherichia coli after 15 mins by scintillation proximity assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 15 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Late stage counterscreen results for the probe development effort to identify inhibitors of gld-1: FRET-based biochemical dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
Assay data:15 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
Assay data:18 Active, 1 Activity ≤ 1 µM, 77 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
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