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Human Factor D Assay from US Patent US11814391: "Macrocyclic compounds for the treatment of medical disorders"
Assay data:51 Active, 49 Activity ≤ 1 µM, 54 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Human Factor D Assay from US Patent US11718626: "Macrocyclic compounds for treatment of medical disorders"
Assay data:220 Active, 216 Activity ≤ 1 µM, 223 Tested
Human Factor D Assay from US Patent US11708351: "Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders"
Assay data:530 Active, 481 Activity ≤ 1 µM, 563 Tested
Factor D Esterolytic Assay from US Patent US11708347: "Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors"
Assay data:536 Active, 25 Activity ≤ 1 µM, 536 Tested
Human Factor D Assay from US Patent US11649229: "Amide compounds for treatment of immune and inflammatory disorders"
Assay data:8 Tested
SummaryRelated BioAssays by Target
Factor D Esterolytic Assay from US Patent US11559515: "Indole compounds and analogues thereof"
Assay data:112 Active, 48 Activity ≤ 1 µM, 377 Tested
Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and measured by colorimetric method based esterolytic assay
Assay data:42 Active, 33 Activity ≤ 1 µM, 55 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Human Factor D Assay from US Patent US11447465: "Pharmaceutical compounds for treatment of medical disorders"
Assay data:101 Active, 82 Activity ≤ 1 µM, 118 Tested
Human Factor D Assay from US Patent US11407738: "Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders"
Assay data:57 Active, 42 Activity ≤ 1 µM, 121 Tested
Factor D Esterolytic Assay from US Patent US11370774: "Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors"
Assay data:503 Active, 475 Activity ≤ 1 µM, 528 Tested
Human Factor B Assay from US Patent US11248000: "Quinazoline and indole compounds to treat medical disorders"
Assay data:23 Active, 18 Activity ≤ 1 µM, 34 Tested
Human Factor D Assay from US Patent US11053253: "Macrocyclic compounds for treatment of medical disorders"
Factor D Assay from US Patent US11084800: "Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders"
Assay data:533 Active, 482 Activity ≤ 1 µM, 565 Tested
Human Factor D Assay from US Patent US11001600: "Disubstituted compounds for treatment of medical disorders"
Assay data:13 Active, 12 Activity ≤ 1 µM, 13 Tested
Human Factor D Assay from US Patent US10919884: "Amide compounds for treatment of immune and inflammatory disorders"
Inhibition Assay from US Patent US10849883: "Benzopyrazole compounds and analogues thereof"
Assay data:329 Active, 265 Activity ≤ 1 µM, 377 Tested
Inhibition Assay from US Patent US10822352: "Aryl, heteroaryl, and heterocyclic compounds for treatment of medical disorders"
Assay data:585 Active, 508 Activity ≤ 1 µM, 703 Tested
TBD from US Patent US10807952: "Compounds for treatment of immune inflammatory disorders"
Assay data:95 Active, 81 Activity ≤ 1 µM, 101 Tested
Inhibition Assay from US Patent US10660876: "Amino compounds for treatment of medical disorders"
Assay data:79 Active, 59 Activity ≤ 1 µM, 89 Tested
Human Factor D Assay from US Patent US10550140: "Ether compounds for treatment of complement mediated disorders"
Assay data:43 Active, 42 Activity ≤ 1 µM, 43 Tested
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